摘要
目的:探讨营养干预对阿尔茨海默病(AD)病人营养状况、认知功能和日常生活活动能力(ADL)的影响。方法:将90例AD病人随机分为对照组和干预组,每组45例。对照组病人给予抗痴呆药物治疗;干预组病人在药物治疗的基础上给予增加肠内营养乳剂(TPF-T)口服营养补充治疗,6个月后分别评估两组病人治疗前后的营养状况、认知功能和ADL,同时观察病人的营养学指标等。结果:治疗6个月后,干预组病人的营养状况、简易精神状态量表(MMSE)、ADL评分、营养学指标明显改善,与对照组比差异有显著性统计学意义(P<0.05)。结论:营养干预能有效改善AD病人的营养状况,并有利于认知功能和日常生活活动能力的提高。
Objective： To explore the effects of nutritional intervention on the nutritional status, cognitive function and activities of daily living （ADL） in patients with Alzheimer＇s Disease （ AD ）. Methods： 90 AD patients were randomly divided into the control group and the intervention group, with 45 cases in each group. Patients in the control group received anti-dementia drugs, and patients in the intervention group additionally received TPF-T as the oral nutritional supplement. The nutritional status and nutritional biochemical indicators, cognitive function and ADL of two groups were evaluated when en- rolled and 6 months later after the treatment. Results ： After 6 months＇treatment, the nutritional status, MMSE, ADL scores and nutritional indicators of patients in the intervention group were significantly im- proved compared to the control group （ P 〈 0.05 ）. Conclusion ： Nutritional intervention can effectively improve the nutritional status, cognitive function and ADL of patients with dementia.
出处
《肠外与肠内营养》
北大核心
2017年第2期75-77,共3页
Parenteral & Enteral Nutrition
关键词
阿尔茨海默病
营养干预
口服营养补充
Alzheimer disease
Nutritional intervention
Oral nutritional supplements
