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中药熏蒸对挂线引流术后肛瘘患者血清免疫球蛋白水平及预后的影响 被引量:22

Effect of Herbal Fumigation on Serum Levels of Immunoglobulin and Prognosis of Patients with Anal Fistula after Hanging Line Drainage Operation
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摘要 目的:探讨中药熏蒸对经挂线引流术后肛瘘患者血清免疫球蛋白水平及预后的影响。方法:收集我院治疗的94例肛瘘患者,随机分为实验组和对照组,每组47例。所有患者行肛瘘挂线术,对照组患者术后采用左氧氟沙星注射液治疗,实验组患者在对照组基础上给予中药熏洗治疗。观察并比较两组患者治疗前后血清IgA及IgG水平,疼痛持续时间及恢复时间以及临床疗效。结果:与治疗前相比,两组患者治疗后血清IgA及IgG水平均下降,差异具有统计学意义(P<0.05);与对照组相比,实验组患者治疗后血清IgA及IgG水平较低,差异具有统计学意义(P<0.05);实验组患者疼痛持续时间及恢复时间均少于对照组,差异具有统计学意义(P<0.05);实验组临床治疗有效率高于对照组,差异具有统计学意义(P<0.05)。结论:中药熏蒸能够降低经挂线引流术后肛瘘患者血清IgA及IgG水平,缩短术后疼痛时间,促进术后康复,临床疗效较好。 Objective: To investigate the effect of herbal fumigation on serum levels of immunoglobulin and prognosis of patients with hal fistula after the hanging line drainage operation. Methods: 94 patients with anal fistula who were treated in our hospital were se- lected and randomly divided into the experimental group and the control group, with 47 cases in each group. All the patients were treated with the hanging line drainage operation. The patients in the control group were treated with routine infusion of levofloxacin injection af- ter the operation, while the patients in the experimental group were treated with herbal fumigation on the basis of the control group. Then the serum levels of IgG and IgA, and the pain duration and recovery time and clinical efficiency of the two groups were observed and compared before and after treatment. Results: Compared with before treatment, the serum levels of IgA and IgG in the two groups de- creased after treatment, and the differences were statistically significant (P〈0.05); Compared with the control group, the serum levels of IgA and IgG in the experimental group were lower after the treatment, and the differences were statistically significant (P〈0.05); The time of pain and recovery in the experimental group were shorter than those of the control group, and the differences were statistically signifi- cant (P〈0.05); The clinical effective rate in the experimental group was higher than that of the control group, and the difference was sta- tistically significant (P〈0.05). Conclusion: Traditional Chinese medicine fumigation can reduce the serum levels of IgA and IgG in pa- tients with anal fistula after the seton drainage operation, which is worthy of clinical application.
作者 王翔 薛昶 邓森田 冯利 薛军 WANG Xian XUE Chan DENG Sen-tian FENG Li XUE Jun(Department of Chinese Medicine of Anorectal, Ankang Central Hospital, Ankang, Shaanxi, 725000, China People's Hospital of Nankai University, Tianjin, 300000, China)
出处 《现代生物医学进展》 CAS 2017年第11期2090-2092,共3页 Progress in Modern Biomedicine
基金 陕西省科学技术研究发展计划项目(201126-08)
关键词 中药熏蒸 挂线引流术 肛瘘 IG A IG G Herbal Fumigation Hanging line drainage Anal fistula IgA IgG
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