摘要
目的:探讨2型糖尿病合并持续性心房颤动(房颤)患者导管消融术后复发的相关危险因素。方法:共入选93例2型糖尿病合并持续性房颤且首次行安贞医院"2C3L"消融术式的患者。消融前检测HbA1c水平。Cox比例风险模型评估房颤复发相关危险因素。结果:中位随访9个月,93例患者中42例(45.2%)房颤复发。Cox多因素回归分析表明左房大小是房颤复发的独立危险因素。ROC曲线分析表明左房大小切点值≥44.5mm预测房颤复发的敏感性为59.5%,特异性为68.6%(AUC=0.665)。结论:左房大小与2型糖尿病合并持续性房颤患者首次导管消融术后复发相关。
Objective：The purpose of this study was to investigate the risk factors associated with recurrence of atrial tachyarrhy!hmia in patients with T2DM and persistent atrial fibrillation undergoing catheter ablation. Method： The study comprised 93 consecutive patients with T2DM and persistent atrial fibrillation who underwent their first catheter ablation. HbAlc levels were measured before ablation. Cox proportional hazards models were constructed to assess risk factors for recurrence of atrial fibrillation. Result： Of the 93 patients, 42 （45.2%） developed AF recurrence after a median 9-month follow-up. Multivariate Cox regression analysis revealed that left atrium size were independent predictors;of recurrent atrial tachyarrhythmia. Receiver operating characteristic analysis demonstrated that an left atrium size of ≥44.5 mm predicted recurrence with 59.5% sensitivity and 68.6% specificity （AUC= 0.665）. Conclusion： Left atrium size was associated with recurrence of atrial tachyarrhythmia in patients with T2DM and persistent atrial fibrillation undergoing catheter ablation.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2017年第4期356-360,共5页
Journal of Clinical Cardiology
关键词
心房颤动
糖尿病
导管消融
atrial fibrillation
diabetes mellitus
catheter ablation
