妊娠期糖尿病合并亚临床甲状腺功能减退孕妇检测血清25-羟基维生素D的意义被引量：23

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摘要目的探讨妊娠期糖尿病(GDM)合并亚临床甲状腺功能减退(SCH)孕妇血清25-羟基维生素D(25-OH-D)表达情况。方法选取GDM合并SCH孕妇298例作为水平观察组,选取同期健康孕妇300例作为对照组。在妊娠24~28周检测空腹血糖(FPG)、促甲状腺激素(TSH)、游离甲状腺素(FT4)、25-OH-D、血钙(Ca^(2+))的水平,并对观察组中不同水平25-OH-D组中FPG、TSH、FT4、Ca^(2+)水平进行比较。结果 GDM合并SCH的患者FPG、TSH水平明显高于对照组,差异有统计学意义(P<0.01);两组FT4水平相比较,差异无统计学意义(P>0.05);GDM合并SCH的患者25-OH-D、Ca^(2+)水平明显低于对照组,差异有统计学意义(P<0.01)。不同25-OH-D水平组FPG、TSH、Ca^(2+)检测情况相比较,差异有统计学意义(P<0.01),且25-OH-D水平与FPG和TSH水平呈负相关,与Ca^(2+)水平呈正相关。结论 GDM合并SCH的患者25-OH-D检测可作为重要的监测指标。

作者廖琪

机构地区北京市顺义区妇幼保健院北京儿童医院顺义妇儿医院

出处《中国妇幼保健》 CAS 2017年第8期1643-1645,共3页 Maternal and Child Health Care of China

关键词妊娠期糖尿病亚临床甲状腺功能减退症 25-OH-D

分类号 R714.25 [医药卫生—妇产科学]

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