摘要
目的探讨重复经颅磁刺激治疗酒精依赖患者的临床效果。方法选取168例酒精依赖患者,随机分为研究组和对照组各86例,研究组接受重复经颅磁刺激治疗,对照组不接受重复经颅磁刺激治疗,共6周,于治疗前及治疗后第6周末对两组患者进行密西根酒精调查表(MAST)、抑郁自评量表(SDS)、焦虑自评量(SAS)评定,在患者出院后6个月末对两组患者进行复饮情况评定。结果治疗后第6周末,两组的MAST、SAS、SDS评分均较治疗前降低(P<0.05)。治疗后第6周末,研究组的MAST、SAS、SDS评分均低于对照组(P<0.05)。在患者出院后6个月末,研究组的复饮率低于对照组(P<0.05)。结论重复经颅磁刺激能显著改善酒精依赖患者的酒精渴求、焦虑抑郁症状,短期内降低复饮率。
Objective To explore the effects of repetitive Transcranial Magnetic Stimulation （rTMS）to treat patients with alcohol dependence. Methods A total of 168 patients with alcohol dependence were randomly divided into study group （ n = 86 ） with rTMS and control group （ n = 86 ） without rTMS for 6 weeks of treatment. They were assessed with Michigan Alcoholism Screening Test（MAST） , Self-rating Depression Scale（SDS） and Self-rating Anxiety Scale（SAS） before treatment and at the 6th weekend of treatment. They were assessed with the rate of relapse at the 6th month end after their leaving hospital. Results The scores of MAST, SAS and SDS in two groups at the 6th weekend of treatment were all significantly lower than those before treatment（P 〈0.05）. At the 6th weekend of treatment, the scores of MAST, SAS and SDS in study group were all significantly lower than those in control group（P 〈 0.05）. At the 6th month end after their leaving, the rate of relapse in study group was significantly lower than that in control group（ P 〈 0.05 ）. Conclusion It＇ s effective for rTMS to improve the drinking desire, anxiety and depressive symptoms of the patients with alcohol dependence, which should decrease the rate of relapse for the patients in the short-term.
出处
《精神医学杂志》
2017年第1期50-52,共3页
Journal of Psychiatry
关键词
重复经颅磁刺激
酒精依赖
焦虑
抑郁
复饮
Repetitive Transcranial Magnetic Stimulation
Alcohol dependence
Anxiety
Depression Relapse
