摘要
目的探讨牙周病患者种植牙手术前后应用盐酸米诺环素软膏的临床效果。方法本研究共包括研究对象106例,均为2013年10月~2016年3月我院收治的牙周炎患者,且均在我院行人工种植牙手术,随机分为研究组和对照组,每组53例（缺失牙58枚）,研究组手术前后应用盐酸米诺环素软膏,对照组手术前用碘甘油,比较两组患者GI、牙齿松动度、PD、伤口愈合良好率、术后感染率、二期手术时种植体丧失骨整合情况。结果治疗后两组GI、牙齿松动度、PD均较治疗前有明显降低,研究组降低的程度明显高于对照组,两组差异有统计学意义（P〈0.05）;研究组的术后感染率低于对照组,两组差异有统计学意义（P〈0.05）;两组伤口愈合良好率、二期手术时种植体丧失骨整合率比较差异无统计学意义（P〉0.05）。结论在牙周病患者种植牙手术前后应用盐酸米诺环素效果显著,可使术后感染发生率明显降低,且不会影响伤口愈合和种植体丧失骨整合。
Objective To investigate the clinical effect of minocycline hydrochloride ointment on periodontal patients before and after dental implant surgery. Methods 106 cases of periodontal patients with dental implantation selected from Oct2013 to Mar 2016 in our hospital were randomly divided into study group and control group, there were 53 cases in each group（58 missing teeth）, minocycline hydrochloride ointment was used in the study group before and after surgery, the control group used iodine glycerin before surgery, GI, tooth mobility, PD, wound healing rate, postoperative infection rate, implant osseointegration loss situation of two groups were compared. Results GI, tooth mobility, PD after treatment were significantly lower than before treatment, the degree of reduction in the study group was significantly higher than the control group, the difference was statistically significant（P〈0.05）. Postoperative infection rate of the study group was lower than the control group, the difference was statistically significant（P〈0.05）. There was no significant difference in would healing rate and implant osseointegration loss between the two groups（P〈0.05）. Conclusion Minocycline hydrochloride before and after dental surgery has significant effect for patients with periodontal disease, it can significantly reduce the incidence of postoperative infection, and will not affect the wound healing and the implant osseointegration loss situation.
作者
刘霆钧
Liu Tingjun.(Stomatology Department,Dongguan People＇s Hospital,Dongguan 52300)
出处
《中国现代医药杂志》
2016年第9期40-42,共3页
Modern Medicine Journal of China
关键词
牙周病
种植牙
盐酸米诺环素
手术
Periodontal disease
Dental implantation
Minocycline hydrochloride
Surgery
