摘要
目的:考察不同品牌输液器对丹参酮Ⅱ_A磺酸钠注射液的吸附性,为临床输液器的选择提供参考。方法:配制临床用输注浓度的丹参酮Ⅱ_A磺酸钠注射液,设置两种不同滴速(30滴/min和60滴/min),分别经5种不同品牌的输液器流出,收集不同时间点的流出液,用HPLC法测定丹参酮Ⅱ_A磺酸钠的浓度,并分别与流经输液器前(0h)的浓度进行比较。结果:相同滴速和不同滴速条件下丹参酮Ⅱ_A磺酸钠注射液流经输液器前、后浓度无显著性差异。结论:5种不同品牌输液器对丹参酮Ⅱ_A磺酸钠注射液没有明显吸附作用。
Objective： To investigate the absorbability of the infusion sets produced by 5 different manufacturers to sulfo tanshinone Ⅱ A sodium injection, so as to provide reference for the choice of infusion sets. Methods：The solution of sulfotanshi none Ⅱ Asodium injection was prepared as the actual concentration used clinically, and flowed through the infusion sets at the flow rates of 30 and 60 drops per minutes. The output solutions of sulfotanshinone Ⅱ A at different time points were collected for concentration detection by HPLC method, and then the obtained detection results were compared with the solution before passing through the infusion sets. Results： There were no significant differences in the concentrations of sulfotanshinone Ⅱ A sodium injections both before and after passing through the infusion sets, either at the identical or different drop rates. Conclusion： The infusion sets made by 5 different manufacturers did not display any significant absorbability to sulfotanshinone Ⅱ a sodium injections.
出处
《药学服务与研究》
CAS
2017年第2期140-142,共3页
Pharmaceutical Care and Research
基金
上海市科学技术委员会科研计划项目(12DZ1930304)
关键词
丹参酮ⅡA磺酸钠注射液
输液器
吸附性
sulfotanshinone Ⅱ A sodium injection
infusion set
absorbability
