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埃索美拉唑联合莫沙必利治疗老年胃食管反流病临床疗效分析 被引量:1

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摘要 目的探讨埃索美拉唑联合莫沙必利治疗老年胃食管反流病(gastroesophageal reflux disease,GERD)的临床疗效。方法选取100例GERD患者作为研究对象,采用随机数字表法分为观察组和对照组,每组50例。对照组患者给予埃索美拉唑治疗,观察组患者给予埃索美拉唑联合莫沙必利治疗,两组患者均连续治疗4周。比较两组患者症状总评分、内镜评分、症状疗效及内镜检查疗效。结果治疗后,观察组患者症状总评分、内镜评分均显著低于对照组(P<0.05);观察组患者症状疗效及内镜检查疗效均显著高于对照组(P<0.05)。结论埃索美拉唑联合莫沙必利治疗老年GERD患者,可有效改善临床症状,提高临床疗效,治疗效果优于单纯使用莫沙必利治疗。
作者 梁金仙
出处 《内科》 2017年第2期237-238,281,共3页 Internal Medicine
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  • 1陆再英,钟南山.内科学.第七版.北京:人民卫生出版社.2008:783-784.
  • 2Chinese Gastroesophageal Reflux Disease Study Group. Value of reflux di-agnostic questionnaires in the diagnosis of gastroesophageal reflux disease[J]. Chin J Dig Dis,2004;5(2) :51-5.
  • 3lrvine EJ,Whitehead WE, Chey WD, et al. Design of treatment trials for functional gastrointestinal disorders [J]. Gastroenterology,2006 ; 130 ( 5 ) : 1538-51.
  • 4Shin JM, Sachs G. Pharmacology of proton pump inhibitors [J]. Curr Gastroenterol Rep, 2008, 10(6): 528-534.
  • 5Tanaka M, Maruoka A, Chijiiwa Y, et al. Endoscopic ultmsonograph- ic evaluation of gastric ulcer healing on treatment with proton pump irdaibitors versus H2-receptor antagonists [J]. Scand J Gastroenterol, 1994, 29(12): 1140-1144.
  • 6Cho YK, Choi MG, Park EY, et al. Effect of mosapride combined with esomeprazole improves esophageal peristaltic function in pa- tients with gastroesophageal reflux disease: a study using high reso- lution manometry [J]. Dig Dis Sci, 2013, 58(4): 1035-1041.
  • 7Philip O,Lauren B,Marcelo F. Guidelines for the diagnosis and management of gastroesophageal refl ux disease[J].{H}American Journal of Gastroenterology,2013.308-328.
  • 8Vakil N,van Zanten SV,Kahrilas P. The Montreal definition and classification of gastroesophageal reflux disease:a global evidence-based consensus[J].{H}American Journal of Gastroenterology,2006,(08):1900-1920.
  • 9Yaghoobi M,Farrokhyar F,Yuan Y. Is there an increased risk of GERD after Helicobacter pylori eradication:a meta-analysis[J].{H}American Journal of Gastroenterology,2010,(05):1007-1013,1006,1014.
  • 10Malfertheiner P,Megraud F,O'Morain C. Current concepts in the management of Helicobacter pylori infection:the Maastricht III Consensus Report[J].{H}GUT,2007,(06):772-781.

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