摘要
目的探讨松龄血脉康胶囊联合非洛地平片治疗高血压的临床疗效。方法选取2015年10月—2016年10月在上海市杨浦区五角场街道社区卫生服务中心接受治疗的高血压患者86例为研究对象,根据治疗方案的不同分为对照组和治疗组,每组各43例。对照组口服非洛地平片,1片/次,2次/d。治疗组在对照组基础上口服松龄血脉康胶囊,3粒/次,3次/d。两组患者均治疗4周。观察两组的临床疗效,比较两组的生活质量评分和血压变化。结果治疗后,对照组和治疗组的总有效率分别为81.40%、97.67%,两组比较差异有统计学意义(P>0.05)。治疗后,两组躯体症状评分均显著下降,而健康愉快感评分、工作表现评分和生活满意度评分均显著升高,同组治疗前后比较差异有统计学意义(P<0.05);且治疗组这些观察指标的改善程度明显优于对照组,两组比较差异具有统计学意义(P<0.05)。治疗后,两组患者收缩压(SBP)和舒张压(DBP)均明显降低,同组治疗前后比较差异有统计学意义(P<0.05);且治疗组这些观察指标的降低程度明显优于对照组,两组比较差异具有统计学意义(P<0.05)。结论松龄血脉康胶囊联合非洛地平片治疗高血压具有较好的临床疗效,可明显提高患者生活质量,降低患者血压,具有一定的临床推广应用价值。
Objective To investigate the clinical effect of Songling Xuemaikang Capsules combined with Felodipine Tablets in treatment of hypertension.Methods Patients （86 cases） with hypertension in Shanghai Yangpu District Wujiaochang Street Community Health Service Center from October 2015 to October 2016 were enrolled in this study. According to the difference treatment plan, patients were divided into control and treatment groups, and each group had 43 cases. Patients in the control group werepo administered with Felodipine Tablets, 1 tablet/time, twice daily. Patients in the treatment group werepo administered with Songling Xuemaikang Capsules on the basis of the control group, 3 grains/time, three times daily. Patients in two groups were treated for four weeks. After treatment, the clinical efficacies were evaluated, and quality of life scores and blood pressure change in two groups were compared.Results After treatment, the clinical efficacies in the control and treatment groups were 81.40% and 97.67%, respectively, and there was difference between two groups （P 〈 0.05）. After treatment, the somatic symptoms scores in two groups were significantly decreased, but the scores of health pleasure, job performance and life satisfaction, and the difference was statistically significant in the same group （P〈0.05）. And the observational indexes in the treatment group were significantly better than those in the control group, with significant difference between two groups （P〈0.05）. After treatment, SBP and DBP in two groups were significantly decreased, and the difference was statistically significant in the same group （P〈0.05）. And the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups （P〈0.05）.Conclusion Songling Xuemaikang Capsules combined with Felodipine Tablets has clinical curative effect in treatment of hypertension, can significantly improve the quality of life of patients, and reduce blood pressure, which has a certain clinical application value.
出处
《现代药物与临床》
CAS
2017年第4期613-616,共4页
Drugs & Clinic
关键词
松龄血脉康胶囊
非洛地平片
高血压
生活质量评分
血压
Songling Xuemaikang Capsules
Felodipine Tablets
hypertension
quality of life score
blood pressure
