摘要
报告1例早期胃癌内镜下黏膜切除术(endoscopic mucosal resection,EMR)术后异时性远处转移病例、复习国内外相关文献并讨论.对此患者诊治过程进行详细论述,包括实验室检查、影像检查、内镜结果、病理学检查和治疗方案等.该患者给予"FOLFOX4"方案(奥沙利铂85 mg/m^2,静脉滴入,2 h,d1;亚叶酸钙200 mg/m^2,静脉滴入,2 h,d1-d2;5-FU 400 mg/m^2,静脉推注,d1-d2;5-FU 600 mg/m^2持续静脉滴入22 h,d1-d2;每2 wk重复)化疗12周期及"甲磺酸阿帕替尼"靶向治疗后达到部分缓解.
Here we report a case of postoperative metachronous distant metastasis after endoscopic mucosal resection（EMR） for early gastric cancer.The process of diagnosis and treatment is described in detail,with data including laboratory tests,imaging examinations,endoscopic findings,pathological examinations,and treatment plan reported.The patient received 12 cycles of chemotherapy with the FOLFOX4 regimen[oxaliplatin 85 mg/m^2 as a 2-h infusion on day1 and a 2-h infusion of LV 200 mg/（m^2·d） followed by a 5-fluorouridine bolus 400 mg/（m^2·d） and22-h infusion 600 mg/（m^2·d） for 2 consecutive days every 2 wk]and apatinib,and a partial response was achieved.This case suggests that,as a treatment for early gastric cancer,EMR may not completely resect the lesions and cannot handle metastatic lymph nodes.Its clinical effects remain controversial.
作者
周萌
魏晓艳
李颖霞
温洪涛
Meng Zhou Xiao-Yan Wei Ying-Xia Li Hong-Tao Wen(Department of Gastroenterology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, He＇nan Province, Chin)
出处
《世界华人消化杂志》
CAS
2017年第11期1037-1042,共6页
World Chinese Journal of Digestology
关键词
早期胃癌
内镜下黏膜切除术
异时性转移
Early gastric cancer
Endoscopic mucosal resection
Metachronous metastasis
