摘要
目的分析并评价咸阳地区抗高血压药物的使用情况,为促进该类药物的临床合理使用提供参考依据。方法对咸阳市区6家医院2013年10月—2014年10月心血管内科高血压病人住院病例中抗高血压药物具体数据进行统计分析。结果6家医院抗高血压药物品种使用按用药频度(DDDs)排序依次为钙离子通道阻滞剂(CCB)、血管紧张素Ⅱ受体拮抗剂(ARB)、血管紧张素转化酶抑制剂(ACEI)、β-受体阻滞剂和利尿剂。降压治疗方案多采取联合用药,以两联方案居多(占比49.76%),但社区医院主要是以单一用药(占比57.49%)和两联方案(占比37.84%)为主,联合用药方案中以CCB+ARB联合应用最为常见。结论咸阳市区6家医院的抗高血压药物使用基本符合指南要求,但仍存在社区医院药品品种有限、联合用药占比较小等不足之处,仍有待于进一步规范,提高合理用药水平。
Objective To analyze and evaluate the application of antihypertensive drugs in Xianyang,which as a reference for improving the rational use of antihypertensive drugs in clinics. Methods Data of antihypertensive drug use among hypertensive patients admitted to hospital in Department of Cardiovascular Medicine of six hospital in Xianyang from October 2013 to October 2014 were analyzed. Re-sults According to the daily defined doses （DDDs） , the top five antihypertensive drugs classification were calcium channel blockers （CCB） ,angiotensin receptor blockers （ARB） ,angiotensin converting enzyme inhibitors （ACEI ） ,beta-blockers and diuretics. Adoption of combined antihypertensive drug treatment was frequently used in which two-drug therapy （49. 76% ） was most common. In communi-ty hospitals single drug therapy （57.49% ） and two-drug therapy （37. 84% ） were frequently used. The combination of CCB and ARB is most commonly seen in combined drug regimen. Conclusions The use of antihypertensive drugs in 6 hospitals in Xianyang are basi-cally consistent with the guidelines, but there still exist some weaknesses, such as limited drug classification in community hospital and relatively low proportion of drug combination, which needs to be further standardized for rational use of drugs.
出处
《安徽医药》
CAS
2017年第4期747-751,共5页
Anhui Medical and Pharmaceutical Journal
关键词
高血压
抗高血压药
用药频度
Hypertension
Antihypertensive d ru gs
DDDs
