摘要
目的调查分析青海省藏、汉族成年居民血脂水平及其异常检出率的差异,为该地区血脂异常的防治提供依据。方法选取青海省藏(3 343例)、汉族(3 842例)体检者共7 185例为调查对象,测定血清总胆固醇(total cholesterol,TC)、甘油三酯(triglyceride,TG)、低密度脂蛋白胆固醇(low-density lipoprotein cholesterol,LDL-C)、高密度脂蛋白胆固醇(high-density lipoprotein cholesterol,HDL-C)4项指标,分析藏、汉族血脂异常的特点,并比较两民族血脂异常检出率的差异。结果血脂异常总的患病率为49.1%,高于国内平原地区,藏族低于汉族(45.3%vs52.3%);两组人群中,血脂异常的发生率均随着年龄的增加而增高;55岁以前男性血脂异常的发生率高于女性(P<0.05);藏族TC、LDL-C水平高于汉族(P<0.05),而TG和HDL-C水平低于汉族(P<0.05);藏族以高TC血症为主,汉族以高TG血症为主,两组中低HDL-C血症的发生率均为最低。结论青海省藏、汉族血脂异常的发生率高于平原地区,藏族呈"高TC、高LDL-C"、汉族呈"高TG"血脂分布特点,血脂异常的发生率在年龄、性别、民族间存在差异,应重视高原人群的血脂筛查及干预工作,降低血脂异常的患病率,预防心脑血管事件发生。
Objective To investigate the differences in serum lipid levels between Tibetan and Han residents in Qinghai province and to provide evidence for the prevention and treatment of dyslipidemia.Methods A total of 7 185 participants （Tibetan 3 343,Han 3 842） were enrolled in this study.Fasting plasma levels of total cholesterol （TC）,triglyceride（TG）,high-density lipoprotein cholesterol （HDL-C）, and low-density lipoprotein cholesterol （LDL-C） were tested.Results The overall prevalence of dyslipidemia was 49.1%, which was higher than that in plains at home.The prevalence rate in Tibetan was lower than that in Han residents（45.3% vs 52.3%）.The rate of dyslipidemia increased with age both in Tibetan and Han residents.Moreover, the rate of dyslipidemia was higher in males than in females before 55 years old（P〈0.05）.TC and LDL-C levels in Tibetan were higher than those in Han residents（P〈0.05）, while TG and HDL-C levels were significantly lower（P〈0.05）.The majority of Tibetans was hypercholesterolemia, the Han nationality was hypertriglyceridemia.However, the incidence of low HDL-C in two groups were the lowest.Conclusion Compared with plain areas of China, the prevalence of dyslipidemia was higher in Qinghai-Tibet plateau.Tibetans had higher TC and LDL-C while the Han nationality had higher TG.The prevalence of dyslipidemia was different in age, nationality and sex.In order to reduce the prevalence rate, more attention should be paid to the screening and prevention of dyslipidemia in the high altitude area.
出处
《临床荟萃》
CAS
2017年第5期413-415,420,共4页
Clinical Focus
基金
青海省卫生和计划生育委员会指导性课题(2015-N-003)
关键词
血脂异常
人种群
汉族
藏族
高原
dyslipidemia
ethnic groups
han nationality
zang nationality
plateau
