摘要
目的对米非司酮、宫腔镜联合腹腔镜技术用于剖宫产术后子宫瘢痕妊娠治疗的安全性进行研究,为临床治疗提供数据支持。方法将研究选取的137例研究对象采用随机数字表法分为2组,观察组69例,采用米非司酮、宫腔镜联合腹腔镜技术治疗;对照组68例,采用宫腔镜联合腹腔镜技术治疗。术后就治疗成功率,手术时间,安全性,术中出血量,阴道流血时间、血β-HCG恢复时间、月经恢复时间等数据进行组间比较及统计学分析。结果观察组治疗成功率为98.6%,对照组治疗成功率为88.2%,观察组显著优于对照组(P<0.05);2组并发症发生率分别为18.8%和26.5%,观察组显著低于对照组(P<0.05);观察组的手术时间、术中出血量、阴道流血时间及住院时间等数据分别为(22.6±4.5)min、(32.5±5.6)ml、(18.2±5.3)d和(12.5±2.6)d均显著优于对照组(P<0.05);观察组血β-HCG和月经恢复时间分别为(32.8±6.3)d和(28.6±4.8)d均显著优于对照组(P<0.05)。结论米非司酮、宫腔镜联合腹腔镜技术用于剖宫产术后子宫瘢痕妊娠治疗具有成功率高,安全性高,客观指标改善显著,不影响月经恢复等优势,具有推广价值。
Objective To study the safety of mifepristone and hysteroscopy combined with laparoscopy in the treatment of uterine scar pregnancy after cesarean section, and to provide data for clinical treatment.Methods Using random number table method, 137 subjects were selected and divided into two groups： the observation group （69 cases） treated with mifepristone and hysteroscopy combined with laparoscopy, and the control group （68 cases） treated with hysteroscopy combined with laparoscopy. After operation, the success rate, duration of surgery, safety, intraoperative blood loss, duration of vaginal bleeding, bloodβ-HCG recovery time, menstrual recovery time and other data were compared between the two groups and statistically analyzed.Results The success rate was 98.6% in the observation group and 88.2% in the control group. The therapeutic effect in the observation group was significantly better than in the control group （P〈0.05）. The incidence of complications was 18.8% in the observation group and 26.5% in the control group （P〈0.05）. In the observation group, the duration of surgery, intraoperative bleeding volume, duration of vaginal bleeding, hospital stay were respectively （22.6±4.5） min, （32.5±5.6） ml, （18.2±5.3） d and （12.5±2.6） d, which were significantly better than in the control group （P〈0.05）. In the observation group, bloodβ-HCG and menstrual recovery time were （32.8±6.3） d and （28.6±4.8） d respectively, which were significantly better than in the control group （P〈0.05）.Conclusion Mifepristone, hysteroscopy combined with laparoscopy technique can ensure a high success rate for the treatment of uterine scar pregnancy after cesarean section. This approach is safe, effective without affecting the menstrual recovery.
出处
《空军医学杂志》
2017年第2期136-138,共3页
Medical Journal of Air Force
基金
2016年湖北医药学院附属医院院级基金项目(2016JJXM087)
关键词
米非司酮
宫腔镜
腹腔镜
剖宫产术后子宫瘢痕妊娠
生育功能
mifepristone
hysteroscopy
laparoscopy
uterine scar pregnancy after cesarean section
reproductive function
