摘要
目的:观察西黄胶囊治疗轻中度癌性疼痛的临床疗效。方法:将60例轻度癌痛患者随机分为治疗组和对照组,每组各30例,对照组给予塞来昔布胶囊,治疗组给予西黄胶囊。将64例中度癌痛患者随机分为治疗组和对照组,每组各32例。对照组给予盐酸曲马多缓释胶囊,治疗组在对照组的基础上给予西黄胶囊。观察各组的临床疗效,生活质量疗效、止痛起效时间及维持时间。结果:轻度癌痛患者治疗组效率为83.3%,对照组有效率为86.7%,两组有效率比较,差异无统计学意义(P>0.05);治疗组止痛起效时间为(4.26±0.81)h,对照组为(1.43±0.67)h,差异具有统计学意义(P<0.01),但两组止痛维持时间比较,差异无统计学意义(P>0.05);两组生活质量疗效比较,差异无统计学意义(P>0.05)。中度癌痛治疗组有效率为84.4%,对照组有效率为65.6%,两组患者临床疗效比较,差异具有统计学意义(P<0.05);治疗组止痛起效时间(39.11±9.65)min,短于对照组的(45.36±9.44)min,两组比较,差异具有统计学意义(P<0.05);治疗组止痛维持时间为(10.52±1.58)h,长于对照组的(9.56±1.55)h,差异具有统计学意义(P<0.05);两组生活质量疗效比较,差异具有统计学意义(P<0.05)。结论:西黄胶囊可单独运用于轻度癌性疼痛,起效时间稍长;对于中度疼痛,西黄胶囊联合西药止痛剂可以提高止痛疗效,缩短起效时间,延长止痛维持时间,且可提高患者生活质量。
Objective： To observe the clinical effects of Xihuang Capsules on mild and moderate cancer pain. Methods： Totally 60 patients with mild cancer pain were randomized into treatment group and control group, 30 cases in each group. Control group were given Celecoxib Capsules while treatment group were given Xihuang Capsules. Totally 64 patients with moderate cancer pain were randomized into treatment group and control group, 32 cases in each _group. Control group were given Tramadol Hydrochlo- ride Capsules while treatment group were additionally given Xihuang Capsules for the treatment. The clinical effects, life quality, the onset time of pain checking and duration of the effects in each group were observed. Results： Among patients with mild cam：- er pain, the effective rate was 83.3% in treatment group and 86.7% in control group; there was no statistical diterenee （ P 〉 0.05）. The onset time of pain checking was （4.26±0. 81 ） h in treatment group and （ I. 43± 0.67 ） h in control group; the difference had statistical significance （P 〈 0.01 ）, but there was no difference in duration of pain checking in both gl＇oups （P 〉 0.05）. The diftrence in life quality efficacy had no statistical significance （ P 〉 0.05 ）. Among patients with moderate cancer pain, the effective rate was 84.4% in treatment group and 65.6% in control group; with statistical ditercuce （ P 〈0.05 ）. The onset time of pain checking was （39.11 ± 9.65 ） rain in treatment group , lower than （45.36 ± 9.44） rain in control group ; the difference had statistical significance （P 〈 0.05 ）. The duration of pain checking was （ 10.52 ± 1.58 ） h in treatment group and （9.56 ±1.55） h in control group; the difference had statistical significance （P 〈 0.05 ）. The difference in life quality efficacy had statistical significance （P 〈 0.05）. Conclusion： Xihuang Capsules can be singly applied to mild cancer pain with relatively loug onset time and few adverse reactions. For moderate pain, Xihuang Capsules combined with analgetics of western medicine can enhance tile effects of checking pain, shorten the onset time, prolong the duratiou of pain checking and enhance the patients＇ life quality.
出处
《河南中医》
2017年第5期908-910,共3页
Henan Traditional Chinese Medicine
关键词
癌性疼痛
西黄胶囊
轻度
中度
cancer pain
Xihuang Capsules
mild pain
moderate pain
