摘要
目的探讨持续性透析(MHD)患者矿物质和骨代谢紊乱与高敏C反应蛋白(hs-CRP)水平的关系。方法选择2015年10月~2016年10月在我院血透室进行MHD的78例患者,测定其hs-CRP水平以及矿物质和骨代谢相关指标[血钙(Ca)、血磷(P)和甲状旁腺素(PTH)],统计患者的透析充分性,采用多元线性回归分析hs-CRP水平与Ca、P和PTH的关系。结果 78例患者中,24例达到了美国肾脏病患者生存质量指南(K/DNOQI)推荐的电解质标准,达标率为30.77%(24/78)。达标组与未达标组间的hs-CRP水平比较,差异有统计学意义(P<0.05)。hsCRP水平与血P水平成正相关,与血Ca和PTH水平无相关性。结论 MHD患者矿物质和骨代谢紊乱与hs-CRP水平高度相关,血P为hs-CRP水平增高的危险因素。
Objective To investigate the relationship of mineral and bone disorder with high sensitivity C reactive pro-tein （hs-CRP） in maintenance hemodialysis patients.Methods 78 patients with maintenance hemodialysis from hemodial- ysis room in our hospital from October 2015 to October 2016 were selected,the level of calciumion （Ca）,phosphorus （P） and parathyroid hormone were determined,the hemodialysis sufficiency were calculated.The relationship of level of Ca,P and PTH with hs-CRP were investigated by multiple linear regression analysis.Results In 78 patients,24 cases reached K/DNOQI electrolyte standards,compliance rate was 30.77% （24/78）.There was significant difference in hs-CRP level between the standard group and the substandard group （P〈0.05）.The level of hs-CRP were positive correlated with P and did not correlate with level of Ca and PTH.Condusion There is a close correspondence between mineral am bone disorder and hs-CRP, the level of P is independently an increased risk for hs-CRP.
作者
秦艳东
晏文芬
吴小兰
李敏晖
周国用
QIN Yan-dong YAN Wen-fen WU Xiao-lan LI Min-hui ZHOU Guo-yong(Department of Nephrology,the Third People＇s Hospital of Nanhai District of Foshan City in Guangdong Province,Foshan 528244,Chin)
出处
《中国当代医药》
2017年第13期57-59,共3页
China Modern Medicine
基金
广东省佛山市医学类科技类攻关项目(2016AB000852)
关键词
持续性透析
高敏C反应蛋白
慢性肾脏病
骨代谢紊乱
Maintenance hemodialysis
High sensitivity C reactive protein
Chronic kidney disease
Bone disorder
