摘要
目的探讨TORCH抗体检测的临床意义。方法用化学发光微粒子免疫检测法(CMIA)检测血清中的特异性抗弓形虫IgM/IgG抗体(TOX-IgM/IgG)、抗风疹病毒IgM/IgG抗体(RV-IgM/IgG)、抗巨细胞病毒IgM/IgG抗体(CMV-IgM/IgG),检测抗单纯疱疹病毒Ⅰ型和Ⅱ型IgM/IgG抗体(HSVⅠ/Ⅱ-IgM/IgG),分析感染率。结果与育龄妇女相比,新生儿的TOX、RV、CMV的IgM抗体阳性率均降低,差异有统计学意义(P<0.05),其余2项差异无统计学意义。新生儿的RV-IgG阳性率低于育龄妇女,差异有统计学意义(P<0.01),其余4项差异无统计学意义(P>0.05)。结论 TORCH的筛查对做好优生优育工作、提高出生人口素质具有重要意义。
Objective To to investigate the clinical significance of TORCH antibody detection. Methods Chemiluminescence particles immunoassays（CMIA） was adopted to detect the clinical serum specimens for specific TOX plasma gondii IgM/IgG antibodies（ TOX - IgM/IgG）, rubella virus IgM/IgG antibodies （RV - IgM/IgG）, IgM/IgG antibodies against cytomegalovirus （ CMV - IgM/IgG）, HSV I - IgM/IgG and HSV lI - IgM/IgG, so as to analyze the infection rates of TORCH statistically. Results Compared with women of child - beating age group, the positive rates of TOX - IgM, RV - IgM and CMV - IgM in the neonates significantly decreased, with the differences statistically significant（ P 〈 0.05 ） , while the differences on the other two items were not statistically significant. The positive rate of RV - IgG in the neonates group was significantly lower than the women at child- beating age, with the differences statistically significant（ P 〈 0.01 ）. While, the differences on the rest items were not statistically signifficant （ P 〉 0.05 ）. Conclusion TORCH detection is very meaningful for promoting good prenatal and postnatal care as well as improving the quality of birth population.
作者
梁宇
马琳娜
LIANG Yu MA Lin -na(Clinical Laboratory, Women＇s Hospital Affiliated to Medicine School of Zhejiang University, Hangzhou, Zhejiang 310000, China)
出处
《中国卫生检验杂志》
CAS
2017年第9期1274-1275,1278,共3页
Chinese Journal of Health Laboratory Technology
基金
杭州医学院校级A类项目(2015XZA05)
关键词
TORCH感染
育龄妇女
新生儿
TORCH infection
Women of child - bearing age
Neonates
