摘要
目的观察全身少见部位神经内分泌癌的CT与MRI表现,提高对其认识。方法回顾性分析经病理证实的18例神经内分泌癌患者的临床及CT与MRI资料。8例行CT检查,其中4例行CT增强扫描;17例行MRI检查,其中13例行动态增强扫描。结果位于鼻腔鼻窦7例,子宫6例,卵巢1例,乳腺3例,肾脏1例。11例边界清晰,7例边界欠清。CT表现:软组织密度影,病变周围明显骨质破坏及转移灶,增强扫描病灶呈中等程度强化。MRI表现:7例呈长T_1、长T_2信号,3例呈等T_1、稍长T_2,3例呈稍长T_1、混杂长T_2信号,1例呈等T_1、等T_2信号,3例子宫颈内膜不均匀增厚未见明显异常信号。4例DWI高b值弥散受限呈稍高信号,11例弥散受限呈高信号,2例未见明显受限,平均ADC值为(0.64±0.12)×10^(-3)mm^2/s。增强扫描可见病变呈中等程度强化。时间-信号强度曲线:流入型2例,平台型3例,流出型8例。结论少见部位神经内分泌癌CT与MRI具有一定特征性改变,CT结合MRI检查可明确病变的范围及有无转移,通过MRI动态增强可以了解病变的血供情况,有利于明确诊断并协助临床医师制定治疗方案。
Objective To observe the CT and MRI features of neuroendocrine carcinoma in rare sites,in order to im- prove the diagnosis of this disease. Methods The clinical and imaging manifestations of neuroendocrine carcinoma demonstrated by pathology in 18 patients were analyzed retrospectively. There were 6 males and 12 females with mean age of 45.1 years old, ranging from 28 -79. 8 patients underwent CT and 3 of them with enhancement scan. 17 patients under-went MRI scan and 13 of then with enhancement scan. Results The lesions were located in the sinonasal （n= 7） ,uterus （ n = 6 ） , ovary （ n = 1）, breast （ n = 3 ） and renal （ n = 1 ）. 11 of 18 lesions showed clear boundaries and 7 of them had obscure boundaries. On CT images, the lesions showed soft tissue density and bony resorption or metastases. After injection of contrast agent ,the lesions showed moderate enhancement. On MRI images, 7 patients had long T1 and long T2 signals, 3 patients with isointense T1 single and slightly long T2 single . 3 of patients with slightly long T1 signal and heterogeneous long T2 signal, including one patient with isointense T1 and T2 signal. 1 patient with no abnormal signal only had uneven cervical endometrial thicken. DWI showed distinct diffusion restriction with slight（ n = 4 ） or high （n = 11 ） signal. 2 of them showed no diffusion restriction. The mean ADC of the lesions was （0.64±0.12）×10^-3mm^2/s. The time-signal intensity curve types were measured, type Ⅰ（ n = 2 ）, type Ⅱ（ n = 3 ） ,type Ⅲ（ n = 8 ）. Conclusion Concerning the characteristics of rare sites of neuroendocrine carcinoma, CT combined with MRI could accurately demonstrate the range of the lesion ,the invasive extent or whether the lesion metastasized. By use of dynamic enhanced MRI, the blood supply of the lesion could be exhibited. Therefore, CT combined with MRI can provide more comprehensive information in the diagnosis and therapy of neuroendocrine carcinoma of rare sites.
出处
《临床放射学杂志》
CSCD
北大核心
2017年第4期471-474,共4页
Journal of Clinical Radiology
关键词
神经内分泌癌
影像学
Rare sites neuroendocrine carcinoma Imaging features
