摘要
目的研究与分析妊娠期糖尿病产妇产后糖尿病发生情况及危险因素。方法选取2014年5月-2016年2月期间温州医学院附属温岭医院的315例妊娠期糖尿病产妇为研究对象,将其产后糖尿病发生率进行统计,并比较不同妊娠前因素(年龄、BMI值、糖尿病家族史、WHR)及妊娠中及产后因素(血脂、血压、孕期空腹血糖、发病时间、孕期活动量及分娩后体重)者其产后糖尿病的发生率,同时以Logistic分析上述因素与产后糖尿病发生的关系。结果 315例妊娠期糖尿病产妇产后发生糖尿病33例,发生率为10.48%,年龄较高、BMI值较高、存在糖尿病家族史、WHR较高、高血脂、高血压、孕期空腹血糖较高、孕早期发病、孕期未锻炼及分娩后体重升高者的产后糖尿病发生率明显高于年龄较低、BMI值较低、无糖尿病家族史、WHR较低、无高血脂、无高血压、孕期空腹血糖较低、孕中期及孕晚期发病、孕期锻炼及分娩后体重未升高者,且经Logistic分析显示,年龄(OR=9.421,95%CI:2.467~32.563)、BMI值(OR=2.994,95%CI:1.976~14.568)、糖尿病家族史(OR=8.721,95%CI:2.253~31.563)、WHR(OR=8.104,95%CI:2.015~30.567)、血脂(OR=5.281,95%CI:2.087~22.637)、血压(OR=4.211,95%CI:1.993~18.524)、孕期空腹血糖(OR=1.052,95%CI:1.015~3.142)、发病时间(OR=0.375,95%CI:0.141~1.252)、孕期活动量(OR=0.948,95%CI:1.256~10.251)及分娩后体重(OR=1.161,95%CI:1.134~3.567)均与产后糖尿病的发生有密切的关系(均P<0.05)。结论 2014年5月-2016年2月期间温州医学院附属温岭医院妊娠期糖尿病产妇产后糖尿病发生率较高,且其妊娠前因素、妊娠中及产后因素均是其发生产后糖尿病的重要因素,应给予针对性干预。
Objective To study and analyze the incidence of postpartum diabetes and its risk factors in puerperas with gestation- al diabetes. Methods Three hundred and fifteen puerperas with gestational diabetes hospitalized in the Affiliated Wenling Hos- pital of Wenzhou Medical College from May 2014 to February 2016 were selected as the research objects. The incidence rate of postpartum diabetes in all the puerperas was statistically analyzed, and the incidence rates of postpartum diabetes in puerperas with factors before pregnancy（ age, BMI value, family history of diabetes and waist-to-hip ratio （WHR） ） as well as factors during preg- nancy and after childbirth （ blood lipids, blood pressure, fasting blood glucose during pregnancy, time of onset, exercise during preg- nancy and body weight after delivery） were compared. At the same time ~ the relationship between the above-mentioned factors and the incidence of postpartum diabetes was analyzed by the Logistic analysis. Results There were 33 cases of postpartum diabetes among 315 puerperas with gestational diabetes, with the incidence rate being 10.48%. The incidence rate of postpartum diabetes was significantly higher in puerperas with advanced maternal age, high BMI value, family history of diabetes, high WHR, hyper- lipemia, hypertension, high fasting blood glucose during pregnancy,the onset during early pregnancy, without exercise during preg- nancy and weight gain after delivery than in ones with younger maternal age,low BMI value,without family history of diabetes, low WHR, without hyperlipemia and hypertension, low fasting blood glucose during pregnancy, the onset during the second and third tri- mesters of pregnancy, exercise during pregnancy and without weight gain after delivery ; moreover, the Logistic analysis showed that age （ OR = 9.421,95% CI： 2.467-32.563 ）, BMI value （ OR = 2.994,95 % CI： 1.976-14.568）, family history of diabetes （ OR = 8.721,95%CI：2.253-31.563）, WHR（ OR = 8.104,95% CI： 2.015- 30.567） , blood lipids （ OR = 5.281,95% CI： 2.087-22.637）, blood pressure（ OR = 4.211,95%CI： 1.993-18.524）, fasting blood glucose during pregnancy（ OR= 1.052,95%CI： 1.015-3.142） ,time of onset （ OR = 0.375,95 % CI： 0.141 - 1.252 ）, exercise during pregnancy （ OR = 0.948,95 % CI： 1. 256 - 10.251 ） and body weight after delivery（ OR= 1.161,95%CI： 1.134-3.567） were all closely related to the incidence of postpartum diabetes （all P〈0.05）. Con- dusions The incidence rate of postpartum diabetes in the puerperas with gestational diabetes in the Affiliated Wenling Hospital of Wenzhou Medical College from May 2014 to February 2016 is high; moreover, the factors before pregnancy as well as factors dur- ing pregnancy and after childbirth are all the important factors for the incidence of postpartum diabetes. Therefore, the targeted in- terventions should be conducted.
出处
《实用预防医学》
CAS
2017年第6期696-698,共3页
Practical Preventive Medicine
基金
温岭市科技计划项目(2010WLCB0082)
国家自然科学基金(NO:21177152)
关键词
妊娠期糖尿病
产妇
产后糖尿病
危险因素
gestational diabetes
puerpera
postpartum diabetes
risk factor
