摘要
目的分析减毒活疫苗在预防接种水痘的不良反应。方法收集86例预防接种水痘减毒活疫苗出现不良反应的患儿的临床资料,分析患者不良反应的性别及年龄分布、种类、发生时间、转归情况。结果本组64例出现不良反应的患儿中,不良反应以一般反应为主,其次为异常反应、偶合反应,其中异常反应以过敏性皮疹、过敏性紫癜为主;在接种48 h内与接种48 h之后的不良反应发生率对比,差异具有统计学意义(P<0.05),经对症处理后,预后均良好。结论减毒活疫苗在预防接种水痘的安全性较高,不良反应以一般反应为主,但在接种48 h内,应警惕异常反应、偶合反应的发生,加强监测、及时处理。
Objective To investigate the advorse effects of attenuated live vaccine in preventing vaccination of varicella, Methods The clinical data of 64 cases of children with adolescent vaccination against live attenuated varicella were collected, and the gender and ago distrlbution, type, time and outcome of adverse reactions were analyzed, Result） In this group of 64 cases of adverse reactions in children, the adverse reactions to the general reaction, followed by abnormal reactions, coupling reaction, which abnormal reaction to allergic skin rash, allergic purpura mainly in the 48 h inoculation and inoculation 48 h （P 〈 0.05）. After the symptomatic treatment, the prognosis was good. Conclusion The live attenuated vaccineis safe in the vaccination of varicella, and the adverse reaction is in general reaction, However, within 48 hours after inoculation, the abnormal reaction, the occurrence of the coupling reaction, the monitoring and the timely treatment should be carried out.
作者
李玺琨
禹雪
张雨薇
李贺祥
LI Xikun YU Xue ZHANG Yuwei LI Hexiang(Immunization program, Harbin Centers for Disease Control and Prevention, Harbin Heilongjiang 150056, China College of Art, The Northeast Agricultural University, Harbin Hellongjiang 150030, China Drug Administration, The Fourth Hospital in Harbin, Harbin Heilongjiang 150010, China)
出处
《中国卫生标准管理》
2017年第9期3-4,共2页
China Health Standard Management
基金
黑龙江省哈尔滨市科学技术局课题(2016RAQYJ192)
关键词
水痘
减毒活疫茸
不良反应
vadcella
attenuated live vaccine
adverse reaction
