摘要
目的:分析住院患者质子泵抑制剂(PPI)不合理使用的原因,为合理用药提供参考。方法:抽取2016年11月普通外科、肛肠科、消化内科、心血管内科、神经外科住院患者使用PPI医嘱75份,分析其不合理使用的原因。结果:75份医嘱中不合理使用PPI 25份,合理的50份,其使用合理率为66.67%,其中有1份发生药品不良反应。结论:PPI临床合理使用率偏低,存在过度使用PPI以及未能全面考虑药物相互作用、禁忌证、适应证等因素,应加强或干预PPI的临床不合理使用,促进临床合理用药。
Objective ： To analyze the factors of irrational medication of proton pump inhibitors （PPI） hospitalized Patients and to provide a reference for rational medication. Methods： Choosing randomly 75 medical records of inpa- tients used PPI from general surgical unit, anorectal unit, gastroenterological unit, cardiac surgical unit, neurosurgical unit and analyzing their rationality. Results： There are 25 cases of irrational medication and 50 cases of rational medica- tion, of which 1 case producted adverse drug reaction. The reasonable rate was 66.67%. Conclusion： The reasonable rate of PPI using was low. There was over-use of proton pump inhibitors and failure to fully consider the drug interac- tions, contraindications, indications and so on.Therefore, in order to improve the level of clinical rational drug use, we should strengthene it to interfere with the clinical irrational use of PPI.
出处
《抗感染药学》
2017年第2期264-266,共3页
Anti-infection Pharmacy
关键词
质子泵抑制剂
医嘱
合理用药
proton pump inhibitors
the doctor＇s advice
rational medication
