摘要
目的探讨加用自制中药倒膜治疗面部痤疮的临床治疗效果。方法本次研究以我院2015年1月~2016年1月收治的80例痤疮患者为研究对象,将患者随机分为对照组与治疗组,每组各40例患者。其中,对照组患者采用中药内服加夫西地酸乳膏外涂治疗,每日2次;治疗组患者采取中药内服加自制中药倒膜外敷治疗,每周1次,疗程均为8周。结果治疗后8周,治疗组的痊愈率和有效率分别为30.0%和92.5%;对照组则分别为22.5%和75.0%,两组有效率比较,差异有统计学意义(P=0.034);治疗后4周、8周,治疗组不同类型皮损数量与治疗前比较均显著减少(P<0.05);且治疗后8周的数量显著少于治疗后4周(P<0.05),治疗组中同时患有粉刺、丘疹及脓疱患者27例,对此27例患者不同类型皮损治疗总有效率进行χ~2检验,差异无统计学差异,显效率在4周及8周时均有明显差异(P=0.008、0.042),两两比较粉刺型皮损与丘疹型皮损显效率差异有统计学意义(P=0.002、0.024)。两组患者不良反应均较轻微且短暂。结论中药倒膜外敷加中药内服治疗面部痤疮安全有效。
Objective To study the clinical effect of combined application of self-made traditional Chinese medicine pourmask in the treatment of facial acne. Methods 80 patients with acne who were admitted to our hospital from Jan- uary 2015 to January 2016 were selected as the subjects. The patients were randomly divided into the control group and the treatment group, with 40 patients in each group. Among them, the control group was given oral administration of traditional Chinese medicine combined with topical application of fusidic acid cream, twice a day; the patients in the treatment group were given oral administration of traditional Chinese medicine combined with topical application of self-made TCM pourmask, once a week. The course of treatment was 8 weeks in both groups. Results After treatment 8 weeks, The cure rate and effective rate in the treatment group were 30.0% and 92.5% respectively, and which were 22.5% and 75.0% in the control group respectively. The differences were statistically significant between the two groups （P=0.034）; at 4 weeks and 8 weeks after treatment, the number of different types of skin lesions in the treatment group were significantly lower than those before treatment（P〈0.05）; the number at 8 weeks after treatment was signifi- cantly less than that at 4 weeks after treatment（ P〈0.05 ）. In the treatment group, there were 27 patients with ache, pimples and pustules, and the total effective rate of different types of skin lesions in the 27 patients was test by X2 test, and the difference was not statistically significant. There were significant differences in significant effective rate at 4 weeks and 8 weeks（P=-0.008, 0.042）. The differences were statistically significant in the significant effective rate of acne lesions and papular lesions between the two groups（P=0.002, 0.024）. Adverse reactions in both groups were mild and transient. Conclusion Topical application of traditional Chinese medicine pourmask combined with oral administration of TCM in the treatment of facial acne is safe and effective.
出处
《中国现代医生》
2017年第12期91-94,共4页
China Modern Doctor
基金
浙江省瑞安市科技创新专项资金(MS2015008)
关键词
面部痤疮
中医疗法
中药倒膜
中药内服
Facial acne
TCM treatment
Traditional Chinese medicine pourmask
Oral administration of TCM
