摘要
目的:研究无尾果的化学成分。方法:通过反复硅胶柱色谱、Sephadex LH-20凝胶、半制备高效液相色谱等技术对该药材活性部位进行分离纯化,运用NMR、MS等波谱方法进行结构鉴定。结果:从无尾果乙醇提取物乙酸乙酯部位中分离鉴定了9个黄酮类化合物,分别为:槲皮素(1)、(+)-儿茶素(2)、二氢槲皮素(3)、8-醛基-表儿茶素(4)、表儿茶素-[8,7-e]-4β-(4-羟基苯)-3,4-二羟基-2(3H)-吡喃酮(5)、corbulain Ib(6)、phyllocoumarin(7)、kaempferol-3-O-(6-O-caffeoyl)-galactoside(8)、根皮素-4'-O-β-D-葡萄苷(9)。结论:所有化合物均为首次从该植物中分离得到,并且所有化合物均为首次从该属植物中分离得到。
Objective：To investigate the chemical constituents of Coluria longifolia.Methods：The active parts were isolated with the combination of repeated column chromatography,such as silica gel,Sephadex LH-20,and semi-preparative HPLC,and their structures were determined on the basis of MS,NMR spectroscopic analysis.Nine flavonoids were obtained and their structures were elucidated respectively as quercetin（1）,（＋）-catechin（2）,dihydroquercetin（3）,8-aldehyde-epicatechin（4）,epicatechin-（8,7-e）-4β-（4-hydroxyphenyl）-3,4-dihydro-2（3H）-pyranone（5）,corbulain Ib（6）,phyllocoumarin（7）,kaempferol-3-O-（6-O-caffeoyl）-galactoside（8）,phlorizin-4＇-O-β-D-glucoside（9）.Conclusion：All the compounds are isolated from this plant for the first time,all the compounds are obtained from the Coluria genus for the first time.
作者
高燕萍
朱继孝
吴强
梁健
王洪玲
钟囯跃
GAO Yan-ping ZHU Ji-xiao WU Qiang LIANG Jian WANG Hong-ling ZHONG Guo-yue(Research Center of Natural Resources of Chinese Medicinal Materials and Ethnic Medicine ,Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China Science and Technology College of Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China)
出处
《中药材》
CAS
CSCD
北大核心
2016年第11期2521-2524,共4页
Journal of Chinese Medicinal Materials
基金
江西省教育厅科技计划项目(GJJ150839)
江西民族传统药现代科技与产业发展协同创新中心开放基金项目(JXXT201402021
JXXT201402023)
关键词
无尾果
化学成分
黄酮
结构鉴定
Coluria longifolia Maxim.
Chemical constituents
Flavonoids
Structural identification
