摘要
目的:优选胆石六号汤的最佳提取工艺。方法:以总黄酮、栀子苷含量及干膏率的综合评分为指标,在单因素试验基础上,通过L_9(3~4)正交试验考察加水量、提取时间和提取次数对胆石六号汤水提工艺的影响。结果:最佳提取工艺为加12倍量水,煎煮3次,每次1 h。结论:优选的提取工艺合理可行,为胆石六号颗粒剂的制备提供参考。
Objective: To optimize the extraction process of gallstone VI decoction. Methods: The comprehensive scores of total flavonoids, geniposide content and dry extract rate were used as indicators, the effect of amount of water, ex- traction time and frequency on gallstone VI of water extraction process were observed on the basis of single factor tests through L9 (34) orthogonal design. Results: The optimum process was determined as follows: adding 12 times of water and extracting 1 h for 3 times. Conclusion: This optimized process is reasonable and feasible, which could guide industrial production.
出处
《中国现代中药》
CAS
2017年第5期711-715,共5页
Modern Chinese Medicine
基金
贵州省教育厅自然科学研究项目[黔教合K字(2012)054号]
贵州省科技计划课题[黔科合SY字(2015)3028号]
贵州省药剂学研究生卓越人才培养计划[黔教研合ZYRC字(2014)019]
关键词
胆石六号汤
总黄酮
栀子苷
干膏率
正交试验
Gallstone VI decoction
-total flavonoids
geniposide
dry extract rate
orthogonal experiment