摘要
骨质疏松症是一种以骨密度减小,骨折风险增加为特征的全身代谢性疾病。骨质疏松症的治疗方法一直是研究热点,其中双膦酸盐类药物作为一线的抗骨质疏松药物,对治疗骨质疏松症起着重要的作用。本文将围绕双膦酸盐类抗骨质疏松药物的发展、作用机理、疗效方面展开综述,为今后的研究提供参考。
Osteoporosis is a systemic metabolic osteopathy characterized by low bone mineral density, leading to an increased risk of fractures. The treatment of osteoporosis is a research hotspot nowadays, and bisphosphonate as a first-line drug plays a important role in the treatment of osteoporosis. This paper systematically reviews current research progress of bone resorption inhibitive bisphosphonate, mechanism and clinical effectiveness, which may provide some references for future research.
出处
《中华老年骨科与康复电子杂志》
2017年第3期184-187,共4页
Chinese Journal of Geriatric Orthopaedics and Rehabilitation(Electronic Edition)
基金
国家自然科学基金项目(81572154)
天津市卫生局科技攻关项目(15KG123)
卫生部医药卫生科技发展研究中心(W2013ZT058)
关键词
双膦酸盐
骨质疏松症
治疗结果
Bisphosphonates
Osteoporosis
Treatment outcome
