摘要
目的探讨血清超敏C反应蛋白、血清样淀粉酶A与降钙素原对脓毒症患者的预测价值,为早期发现并及时给予干预措施提供参考。方法选取自2013年1月至2015年12月ICU收治的156例脓毒症患者作为研究对象,根据患者病情将患者分为一般脓毒症组、严重脓毒症组和脓毒症休克组;并根据患者治疗后的预后情况将患者分为预后良好组和预后不良组,分析各组间血清超敏C反应蛋白、血清样淀粉酶A与降钙素原的差异。结果严重脓毒症组和脓毒性休克组患者的降钙素原、超敏C反应蛋白、血清样淀粉酶A水平均高于一般脓毒症组患者,且脓毒性休克组患者的上述指标均高于严重脓毒症组患者。预后良好患者有128例,预后不良患者有28例,预后不良组患者的降钙素原、超敏C反应蛋白、血清样淀粉酶A水平均高于预后良好组,差异有统计学意义(P<0.05)。结论血清超敏C反应蛋白、血清样淀粉酶A与降钙素原对脓毒症患者的病情及治疗预后有良好的预测价值。
Objective Exploring the predictive value of Serum hypersensitive C-reactive protein,serum amylase A and procalcitonin for patients with sepsis,to provide a reference for early detection and timely intervention.Methods 156 cases of sepsis,admitted in intensive care unit,were regarded as research object.They were divided into general sepsis group,severe sepsis group and sepsis shock group,based on the severity of illness.At the same time,they were divided into good prognosis group and poor prognosis group,according to the prognosis of patients after treatment.The difference of serum hypersensitive C-reactive protein,serum amylase and procalcitonin of each group were compared.Results The procalcitonin,hypersensitive C-reactive protein and serum amylase A of severe sepsis group and sepsis shock group was higher than general sepsis group;and the sepsis shock group’s was higher than the severe sepsis group’s.There were 128 patients with good prognosis,and 28 patients with poor prognosis.The procalcitonin,hypersensitive C-reactive protein and serum amylase A of good prognosis patients was less than that of poor prognosis patients’.And the differences were statistically significant（P 〈0.05）.Conclusion Serum hypersensitive C-reactive protein,serum amylase A and procalcitonin has a good predictive value on the severity of illness and prognosis in patients with sepsis.
出处
《哈尔滨医药》
2017年第2期107-108,共2页
Harbin Medical Journal
