摘要
目的研究卡贝缩宫素联合卡前列素氨丁三醇注射液(欣母沛)预防宫缩乏力性产后出血的临床应用效果。方法 60例正常足月妊娠阴道分娩宫缩乏力性产后出血患者作为研究对象,依据就诊编号随机分为对照组和观察组,每组30例。对照组患者给予欣母沛肌内注射治疗;观察组患者在对照组治疗基础上联合注射卡贝缩宫素治疗。比较两组患者产时、产后2h、24h出血量及不良反应情况。结果产时两组患者出血量比较差异无统计学意义(P>0.05);产后2h及24h,观察组患者出血量低于对照组,差异有统计学意义(P<0.05);观察组治疗后不良反应发生率为13.33%,明显低于对照组的40.00%,差异具有统计学意义(P<0.05)。结论卡贝缩宫素联合欣母沛能够有效预防因宫缩乏力所引起的产后出血症状,疗效显著,可在临床推广应用。
Objective To research clinical application effect by carbetocin combined with carboprost tmmethamine injection （Hemabate） in prevention of postpartum hemorrhage caused by uterine inertia. Methods A total of 60 full-term vaginal delivery patients with postpartum hemorrhage caused by uterine inertia as study subjects were divided by admission order into control group and observation group, with 30 cases in each group. The control group received intramuscular injection of Hemabate for treatment, and the observation group received additional carbetocin to therapy in the control group for combined treatment. Comparison was made on intrapartum, postpartum 2 h and 24 h bleeding volume, and adverse r6actions between the two groups. Results There was no statistically significant difference of intrapartum bleeding volume between the two groups （P〉0.05）. In postpartum 2 h and 24 h, the observation group had lower bleeding volume than the control group, and their difference had statistical significance （P〈0.05）. The observation group had obviously lower incidence of adverse reactions as 13.33% than 40.00% in the control group, and their difference had statistical significance （P〈0.05）. Conclusion Combination of carbetocin and Hemahate can effectively prevent postpartum hemorrhage caused by uterine inertia with excellent effect. This method is worth clinical promotion and application.
出处
《中国实用医药》
2017年第13期95-97,共3页
China Practical Medicine
