摘要
目的研究桂枝芍药汤对下肢骨折术后肿胀的治疗效果及对患者炎性因子指标表达的影响。方法选取2013年6月至2014年12月68例在本院骨伤科就诊的下肢骨折患者，按数字表法将所有患者随机分为观察组与对照组，观察组口服桂枝芍药汤进行消肿治疗，对照组采用静脉滴注甘露醇。对比两组患者治疗前后肿胀程度、炎性因子表达水平以及骨密度的临床指标。结果治疗后两组肿胀程度均明显好转，观察组为（4．01±1．09）％、对照组为（4．93±1．68）％，观察组的肿胀程度明显更低；治疗后观察组的IL-1、IL-6水平分别为（0．31±0．16）ng／L、（110．56±27．59）ng／L，明显低于对照组的（0．62．4±O．13）ng，L、（131．77±28．95）ng/L；治疗后对照组BMD下降显著低于观察组。结论桂枝芍药汤用于治疗下肢骨折术后肿胀不仅消肿消炎效果更佳，且无不良反应及毒副作用，值得应用。
Objective To investigate the effect of Guizhi Shaoyao Decoction for swelling after surgeryfor bone fracture of lower limbs and its effect on the patients＇ inflammatory factors. Methods 68 patients with lower extremity fractures treated at our hospital from June, 2013 to December were selected and randomly divided into an observation group and a control group. The observation group orally took Guizhi Shaoyao Decoction for swelling and the control group was intravenously dripped mannitol. The swelling degree, levels of inflammatory factors, and bone density were compared and analyzed. Results After treatment, the swelling degrees of the two groups were significantly improved; the swelling degree was （4.01±1.09）% in the observation group and was （4.93±1.68） % in the control group; the levels of IL-1 and IL-6 were （ 0.31±0.16 ） ng/L and （ 110.56±27.59 ） ng/L in the observation group and were （ 0.62±0.13 ） ng/L and （ 131.77±28.95 ） ng/L in the control group; and the BMD was significantly lower in the control group than in the observation group. Conclusion Guizhi Shaoyao Decoction for swelling after surgery for bone fracture of lower limbs is effective and has no adverse reactions and side effects, so it is worth being clinically generalized.
出处
《国际医药卫生导报》
2017年第11期1763-1765,共3页
International Medicine and Health Guidance News
关键词
桂枝芍药汤
下肢骨折
术后肿胀
疗效
Guizhi Shaoyao decoction
Lower extremity fracture
Postoperative swelling
Curativeeffect
