摘要
目的探讨毛细胞型星形细胞瘤的诊治经验。方法回顾性分析60例经病理证实的毛细胞型星形细胞瘤的临床资料,肿瘤部位:颅后窝39例(小脑蚓部9例,小脑半球29例,脑干1例),脊髓7例,幕上脑叶4例,侧脑室内4例,鞍区6例。病例均接受显微外科手术,根据病变不同部位,选择合适手术入路。结果全切除56例,部分切除4例。部分切除者术后辅助放疗或伽玛刀治疗。随访6个月~10年,全切除者均无复发,部分切除者保持稳定,肿瘤无明显增长。结论毛细胞型星形细胞瘤是最低级别胶质瘤,若能全切除病变,无需辅助治疗,效果良好,预后极佳。对于未能全切除者,辅助放疗或伽玛刀治疗,也能取得良好疗效。
Objective To investigate the treatments of pilocytic astrocytoma. Methods The clinical data of 60 patients with pathologically-proved pilocytic astrocytoma were analyzed retrospectively. The locations of tumor were in the posterior fossa in 39 cases （including cerebellar vermis in 9, cerebellum 29, brainstem 1）, spinal cord in 7, supratentorial cerebral lobes in 4, lateral ventricles in 4 and sellar region in 6. All patients underwent microsurgery. According to the tumor location, the appropriate surgical approach was chosen. Results Total tumor resection was performed in 56 cases and partial resection in 4. The patients with partial resection were treated with adjuvant radiotherapy or gamma knife radiosurgery. All the patients were followed up from 6 months to l0 years, and no recurrence was found in total resection patients. The partial resection patients were stable and the tumor had no significant increase in size. Conclusions For the pilocytic astrocytoma lesions, complete resection without adjuvant therapy can achieve satisfactory postoperative outcome. In the patients without complete resection, adjuvant radiotherapy or gamma knife treatment can also get excellent therapeutic outcome.
作者
李天栋
王国良
梁进华
白红民
张小鹏
杨帅
公方和
高寒
王伟民
Li Tiandong Wang Guoliang Liang Jinhua Bai Hongmin Zhang Xiaopeng Yang Shuai Gong Fanghe Gao Han Wang Weimin(Neuromedical Special Hospital of Guangzhou General Hospital of Guangzhou Command, Guangzhou, Guangdong 510010, China)
出处
《中国微侵袭神经外科杂志》
CAS
2017年第5期220-222,共3页
Chinese Journal of Minimally Invasive Neurosurgery
