摘要
目的分析双歧杆菌治疗婴幼儿秋季腹泻的临床疗效。方法选择2014年6月至2016年6月我院收治的130例秋季腹泻患儿为研究对象,随机分为研究组和对照组各65例。对照组患儿口服蒙脱石散治疗;研究组患儿在此基础上口服双歧杆菌治疗。比较两组患儿的临床疗效、一般临床指标和治疗前后免疫功能变化。结果治疗后,研究组患儿治疗总有效率98.5%,显著高于对照组患儿治疗总有效率76.9%,差异有统计学意义(Z=-2.955,P=0.003)。研究组患儿体温恢复时间、大便恢复时间、腹痛缓解时间和呕吐缓解时间,均显著短于对照组患儿,差异均有统计学意义(P<0.05)。研究组患儿IgA、IgG和CD4^+/CD8^+水平,显著高于对照组,差异有统计学意义(P<0.05)。结论双歧杆菌联合蒙脱石散治疗婴幼儿腹泻,可有效缓解临床症状,改善患儿生活质量。
Objective To analyze the clinical effect of bifidobacterium in treating infants with autumn diarrhea.Methods From June 2014 to June 2016, 130 cases of diarrhea patients were randomly divided into two groups： 65 patients in control group received montmorillonite powder only, while 65 cases in treatment group received bifidobacterium and montmorillonite powder for treatment. The clinical efficacy of two groups of children, general clinical indicators and immune function before and after treatment were compared.Results The clinical effective rate of the experimental group was 98.5%, and it was 76.9% in the control group, the difference was statistically significant （ Z = - 2.955, P = 0.003 ）. In the experimental group, the body temperature, stool recovery time, abdominal pain and vomiting recovery time were significantly shorter than the control group （P〈0.05）. The level of IgA, IgG and CD4^＋/CD8^＋ significantly higher than control group, the differences were statistically significant （P〈0.05）. Conclusions Bifidobacterium combined with montmorillonite powder in treating infantile diarrhea can effectively relieve the clinical symptoms, and the therapeutic effect is significant. It is helpful to improve the daily life of patients and is worthy to be popularized in clinical practice.
作者
陈思逸
原春利
方圆
郭志滔
CHEN Si-yi(Department of paediatrics , Hydropower hospital, Guangzhou , Guangdong , 511340, China)
出处
《齐齐哈尔医学院学报》
2017年第7期764-765,共2页
Journal of Qiqihar Medical University
关键词
双歧杆菌感染
腹泻
婴幼儿
蒙脱石散
Bifidobacterium
Autumn diarrhea
Montmorillonite powder
Infants
