摘要
目的:观察西药、针刺和针刺联合西药治疗小儿疱疹性咽峡炎的疗效差异。方法:将120例疱疹性咽峡炎患儿随机分成西药组、针刺组和针刺联合西药组,每组40例。各组患儿均在对症治疗的基础上,西药组给予利巴韦林颗粒口服治疗,按体质量每日10 mg/kg给药,分3次口服,连续服用3 d;针刺组穴取风池、合谷、曲池、下关、颊车、地仓、少商、商阳,予针刺治疗,每日针刺1次,连续针刺3 d;针刺联合西药组采用西药组和针刺组的治疗,联合口服利巴韦林颗粒和针刺治疗,连续治疗3 d。于治疗后进行临床疗效比较,并于治疗结束后4 d进行随访,比较3组患儿的退热时间、疱疹消退时间和美林口服液使用次数。结果:治疗后,针刺联合西药组总有效率为95.0%(39/40),西药组总有效率为62.5%(25/40),针刺组总有效率为80.0%(32/40),针刺联合西药组优于针刺组和西药组(均P<0.05)。针刺联合西药组退热时间和疱疹消退时间均早于针刺组和西药组(均P<0.05)。针刺联合西药组美林口服液使用次数少于针刺组和西药组(均P<0.05)。结论:针刺联合西药治疗小儿疱疹性咽峡炎比单纯使用针刺和西药能更快退热和消退疱疹,减少美林口服液服用次数,临床疗效更优。
Objective To observe the difference in the therapeutic effects on infantile herpetic angina among the treatments with western medication, acupuncture and the combined therapy of acupuncture and western medication. Methods One hundred and twenty children of herpetic angina were randomized into a western medication group, an acupuncture group and a combined therapy group, 40 cases in each one. Besides the basic treatment with symptomatic support, in the western medication group, ribavirin granules were prescribed for oral administration, 10 mg/kga day, three times a day, for 3 days. In the acupuncture group, acupuncture was applied at Fengchi（GB 20）, Hegu（LI 4）, Quchi（LI 11）, Xiaguan（ST 7）, Jiache（ST6）, Dicang（ST 4）, Shaoshang（LU 11） and Shangyang（LI 1）, once a day, for 3 days. In the combined therapy group, the treatments as the western medication group and the acupuncture group were used, in which, the oral administration with ribavirin granules and acupuncture were adopted for 3 days. The clinical therapeutic effects were compared after treatment and the follow-up visit was conducted since the 4th day at the end of treatment to compare the antifebrile time, herpes relieving time and the use frequency of ibuprofen oral liquid in the children among the three groups. Results After treatment, the total effective rate was 95.0%（39/40） in the combined therapy group, was 62.5%（25/40） in the western medication group and was80.0%（32/40） in the acupuncture group. The result in the combined therapy group was better than those in the acupuncture group and the western medication group, indicating the significant differences（both P〈0.05）. The antifebrile time and the herpetic relief time in the combined therapy group were earlier than those in the acupuncture group and the western medication group, indicating the significant differences（both P〈0.05）. The use frequency of ibuprofen oral liquid in the combined therapy group was lower than those in the acupuncture group and the western medication group, indicating the significant difference（both P〈0.05）. Conclusion The combined therapy with acupuncture and western medication relieve fever and herpes much more quickly and reduces the use frequency of ibuprofen oral liquid as compared with the simple use of acupuncture or western medication in the treatment of infantile herpetic angina, which achieve the much better therapeutic effects.
出处
《中国针灸》
CAS
CSCD
北大核心
2017年第6期613-616,共4页
Chinese Acupuncture & Moxibustion
基金
浙江省中医药适宜技术培育项目:2014 ZP 009
关键词
小儿疱疹性咽峡炎
针刺疗法
随机对照试验
infantile herpetic angina
acupuncture therapy
randomized controlled trial（RCT）
