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胸部低剂量螺旋CT在体检者肺癌筛查中的应用 被引量:44

Application of chest low-dose spiral CT for the screening of lung cancer in physical examinees
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摘要 目的 研究胸部低剂量螺旋CT在体检者肺癌筛查中的应用价值.方法 回顾性分析2013年1月至2016年1月行胸部低剂量螺旋CT肺癌筛查的体检者9762例资料,分析年龄、性别等与肺结节检出率、肺癌检出率的相关性,以及检出肺癌的病理分型、临床分期等.结果 9762例体检者中,肺结节及肺癌检出率分别为58.16%(5678/9762)、0.34%(33/9762).年龄越大肺癌检出率越高,80岁以上组肺癌检出率最高,为1.13%(8/709),60~69岁组为0.36%(6/1641).在检出的33例肺癌中,Ⅰ期22例,Ⅲ期5例,Ⅳ期6例,早期诊断率为66.67%(22/33).与常规胸部螺旋CT扫描比较,低剂量胸部CT扫描辐射剂量明显减低(P〈0.05),且图像能够达到诊断要求.结论 胸部低剂量螺旋CT对肺结节及早期肺癌的检出有较大优势. 体检者尤其是肺癌高危人群行低剂量CT扫描可提高肺癌筛查阳性率. Objective To study the application value of chest low-dose spiral CT for the screening of lung cancer in physical examinees . Methods The data of physical examinees that underwent chest low-dose CT for screening of lung cancer from January 2013 to January 2016 was analyzed, the index included the correlation between age and sex with the detection rate of lung nodules and the detection rate of lung cancer, pathological types and clinical stages of lung cancer and so on. Results 9762 physical examinees underwent chest low-dose spiral CT, the detection rates of pulmonary nodules and lung cancer were 58.16%(5678/9762) and 0.34 % (33/9762) respectively. The detection rate of lung cancer increased with the age, the highest detection rate [1.13 % (8/709)] of lung cancer was found in 80 years old and above, the rate in 60-69 years old group was 0.36%(6/1641). In 33 cases of lung cancer, there were 22 cases in stage Ⅰ, 5 cases in stageⅢ, and 6 cases in stage Ⅳ. Early diagnosis rate was 66.67 % (22/33). Compared with the conventional thoracic spiral CT, the low-dose chest CT had loner radiation dose (P〈0.05), and the image can meet the diagnostic requirement. Conclusions Chest low-dose spiral CT has great advantages in the detection of pulmonary nodules and early stage lung cancer. The application of low-dose CT in physical examinees, especially in high-risk groups of lung cancer, can improve the positive rate of lung cancer screening.
作者 张晓琴 孙德俊 化晓宇 张若楠 Zhang Xiaoqin Sun Dejun Hua Xiaoyu Zhang Ruonan(Department of Medical Imaging, Inner Mongolia Autonomous Region People' s Hospital, Hohhot 010017, China Department of Respiratory and Critical Care Medicine, Inner Mongolia Autonomous Region People 's Hospital, Hohhot 010017, Chin)
出处 《肿瘤研究与临床》 CAS 2017年第5期313-315,321,共4页 Cancer Research and Clinic
关键词 肺肿瘤 肿瘤筛查 检出率 体层摄影术 螺旋计算机 Lung neoplasms Tumor screening Detection rate Tomography,spiral computed
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