卡托普利联合比索洛尔治疗慢性心力衰竭的疗效分析被引量：4

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摘要目的探讨卡托普利联合比索洛尔治疗慢性心力衰竭的疗效。方法将240例慢性心力衰竭患者分为对照组和研究组,各120例。两组均给予卡托普利治疗,起始剂量为6.25 mg,3次/d,逐渐加至50 mg,3次/d,有体液潴留者给予利尿剂治疗。观察组在此基础上给予比索洛尔,起始剂量为1.25 mg,1次/d,逐渐加至10 mg,1次/d。连续治疗12周,比较治疗前后两组心功能等级、6 min步行距离、左心室射血分数(LVEF)、血氨基末端脑钠肽前体(NT-pro BNP)和高敏C-反应蛋白(hs-CRP)水平。结果治疗12周后,研究组总有效率高于对照组(<0.05);6 min步行距离长于对照组(<0.05);LVEF略高于对照组,但差异无统计学意义(>0.05);血浆NT-pro BNP和hs-CRP水平均低于对照组(均<0.05)。结论卡托普利联合比索洛尔治疗慢性心力衰竭可以达到更佳的治疗效果,减轻患者心力衰竭症状,改善预后。

作者黄庆岑镇波

机构地区慈溪市人民医院

出处《现代实用医学》 2017年第5期610-612,共3页 Modern Practical Medicine

关键词慢性心力衰竭卡托普利比索洛尔

分类号 R541.61 [医药卫生—心血管疾病] R972 [医药卫生—药品]

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