摘要
多囊卵巢综合征(PCOS)易出现代谢系统疾病,胰岛素抵抗(IR)和高雄激素血症(HA)为其两大基本特征,是代谢与生殖内分泌系统异常的妇科常见疾病,临床表现呈现多样化及复杂性,合并症和远期并发症繁多,易发生2型糖尿病、高脂血症(HLP)及心血管疾病等,远期威胁正逐渐显露且令人担忧。PCOS患者常以不孕就医,代谢并发症常因发展缓慢、早期临床症状不显而易被忽视,研究者们对PCOS研究最初也往往局限于排卵障碍、月经不调、不孕等方面,故着眼于探讨PCOS患者代谢出现的时期及其异常特点,进一步解读PCOS代谢对生殖的影响及其与中医病因病机、证候的联系。
Polycystic ovary syndrome is easy to occur diseases of metabolic system,with insulin resistance（IR） and hyperandrogenism（HA） as the two basic features. It is the common gynecologic disease with abnormal metabolism and reproductive endocrine system, its clinical manifestations showing the characteristics of diversification and complexity, of various complications and long-term complications, such as the type 2 diabetes mellitus, hyperlipidemia （HLP）, and cardiovascular disease. Long-term threat is gradually revealed. PCOS patients often to seek medical advice for barrenness, while the metabolic complications were unnoticable due to the slow development and the early symptoms are not obvious, while the researchers initially often confined to the research on PCOS ovulation disorders, menstruation to be not moved, infertility and so forth. This paper focused on the metabolism emergence period on patients with polycystic ovary syndrome and their abnormal characteristics, further interpretation of the PCOS metabolic effects on reproductive and its links with the etiology, pathogenesis and syndrome of TCM.
出处
《中国中医基础医学杂志》
CSCD
北大核心
2017年第5期654-656,共3页
JOURNAL OF BASIC CHINESE MEDICINE
基金
国家自然科学基金资助项目(81560783)-滋肾清热利湿化瘀方干预PCOS颗粒细胞影响卵泡发育分子机制研究
江西省科技计划项目(20141BBG70056)-滋肾泻火化瘀利湿法对阴虚型多囊卵巢综合征的干预作用--双盲
随机
安慰剂对照研究
关键词
多囊卵巢综合征
糖脂代谢
远期并发症
中医证候
病机
Polycystic ovary syndrome
Glucolipid metabolism
Long-term complications
TCM syndrome
Pathogenesis
