摘要
椎骨皮质骨的断裂风险会随着年龄的增加而增大,然而目前老龄化对皮质骨断裂影响的机制尚不明确。本文的研究目的是探明脊椎段老龄化对皮质骨应变的影响规律。文中建立了2种不同程度老龄化(中度老龄化和完全老龄化)的有限元脊椎段模型,这些老龄化的脊椎段模型是通过改变椎间盘的几何形状和脊椎各组成部分的材料属性生成的,然后将它们与作者之前研究中的一个健康脊椎段有限元模型进行了对比。为了研究哪一种情况对皮质骨的应变影响更大,本文分别建立了两种有限元模型比较方式:一种只改变脊椎材料属性,另一种只改变椎间盘的几何形状。研究结果表明,皮质骨的应变随着老龄化而增大;相比于椎间盘几何形状改变,脊椎材料属性的改变对皮质骨应变的影响更大。本研究结果或可说明,对于预防和治疗椎骨皮质骨断裂,增强脊椎强度是更有效的方式。
The risk of vertebral cortical shell fracture increases with aging. However, it remains unclear how aging contributes to cortex fracture at present. The aim of this study is to make understanding of the mechanism of how the spinal aging influences the cortical shell strain. Two finite element （FE） models of spinal segments （mildly and fully aged） were created, and then were compared to the FE models of the healthy spinal segment. The FE models of the aged spinal segments were generated by modifying both the geometry of the intervertebral disc （IVD） and the material properties of the spinal components. To find out under which case the cortical shell strain was influenced more, we created two types of FE model comparison methods： one with changes only in the spinal material properties and the other with changes only in the IVD geometry. The results showed that the cortical shell strains increased with aging and that compared to the changes of IVD geometry, the changes of spinal material property have a higher influence on the cortical shell strains. This study may suggest that for the prevention and treatment of vertebral cortex fracture, the augmentation of the vertebral body is a more effective treatment.
出处
《生物医学工程学杂志》
EI
CAS
CSCD
北大核心
2017年第3期371-376,共6页
Journal of Biomedical Engineering
基金
中央高校基本科研业务费专项资金资助(DUT15RC(3)130)
关键词
有限元分析
脊椎
老龄化
皮质骨应变
应变测量
finite element analysis
vertebra
aging
cortex strain
strain measurement
