摘要
目的:探讨排石汤联合坦索罗辛在输尿管结石钬激光术后的应用价值。方法:选择98例输尿管结石患者,按随机数字表法分为观察组与对照组,各49例,均采取钬激光术治疗,术后观察组应用排石汤联合坦索罗辛治疗,对照组仅应用坦索罗辛治疗。比较两组1周及2周的结石排净率、治疗前后的24 h尿生化指标、感染与肾绞痛发生率、住院时间与住院费用、不良反应发生率。结果:观察组术后1周与2周的结石排净率为81.6%、100%,高于对照组(均P<0.05)。两组24 h尿钙、尿酸、尿草酸水平较之治疗前均降低(P<0.05),观察组分别为(3.31±1.17)mmol/24 h、(2.84±0.97)mmol/24 h、(0.22±0.08)mmol/24 h,均低于对照组(P<0.05)。观察组术后肾绞痛发生率10.2%,对照组26.5%(P<0.05)。观察组住院时间与住院费用分别为(6.2±2.5)d、(4167.6±344.1)元,少于对照组(均P<0.05)。两组不良反应发生率差异无统计学意义。结论:钬激光术联合应用排石汤与坦索罗辛治疗输尿管结石,可克服排石不净的缺点,加快排石速度并改善24 h尿生化指标,住院花费减少,安全性高。
Objective To investigate the application value oi Faishi decoction combmeu wltn tamsulosm al- ter holmium laser lithotripsy of ureteral calculi. Methods Ninety-eight cases with ureteral calculi were divid- ed into the observation group and the control group according to the method of random number table （49 cases in each group）. Both groups were treated with holmium laser lithotripsy. After operation, the observation group was treated with Paishi decoction combined with tamsulosin while the control group was treated with tamsulosin alone. The clearance rates of stone, 24 h urine biochemical indexes before and after treatment, incidence rates of infection and renal colic, length of hospital stay, hospitalization costs and incidence of adverse reactions were compared between the two groups at the first and second weeks. Results At the first and second weeks after operation, the clearance rates of stones in the observation group （81.6%, 100%） were higher than control group （P 〈 0.05）. After treatment, the levels of 24 h urine Ca2±, uric acid and urine oxalate were decreased, and the levels in observation group [（3.31±1.17） mmol/24 h, （2.84±0.97） mmol/24 h, （0.22±.08） mmol/24 h] were signifi- cantly lower than those in control group （P 〈： 0.05）. The incidence of renal colic in the observation group（10.2%） was significantly lower than that in the con- trol group （26.5%） （P ± 0.05）. The length of hospital stay and hospitalization costs of observation group[（6.2±2.5） d, （4167.6±344.1） yuan] were less than control group （P 〈 0.05）. The incidence rates of adverse reac- tions showed no significant differences. Conclusion The application of holmium laser lithotripsy combined with Paishi decoction and tamsulosin can avoid residual stones, accelerate the removal of ureteral calculi and im- prove 24h urine biochemical indexes in patients. The hospitalization costs is little, and safety and economy are satisfactory.
出处
《中国中西医结合外科杂志》
CAS
2017年第3期246-249,共4页
Chinese Journal of Surgery of Integrated Traditional and Western Medicine
关键词
输尿管结石
钬激光术
排石汤
坦索罗辛
Ureteral calculi
holmium laser lithotripsy
Paishi Decoction
tamsulosin
