摘要
目的目的探讨血小板平均体积(MPV)联合血浆D二聚体(D-D)检测在肺栓塞(PE)中的价值。方法回顾性分析184名被确诊为PE的患者以及100名门诊体检对照者的MPV及D-D联合检测在PE中的应用价值。结果本研究对PE组及对照组临床参数进行比较,发现吸烟比例、MPV及血浆D-D水平等PE组比对照组明显升高,差异有显著性(P<0.05);对PE中影响因素进行多因素Logistic回归分析显示MPV及血浆D-D是PE的独立危险因素;本研究还对MPV及血浆D-D单项检测与联合检测敏感性及特异性进行比较,联合检测结果真阳性率(χ~2=38.18,P=0.031)、真阴性率(χ~2=56.02,P=0.012)均具有统计学意义。结论血常规检查中的MPV联合血浆D-D检测在PE中一定的诊断价值,可作为PE筛选指标。
Objective To investigate the diagnostic importance of mean platelet volume （MPV）and D- dimer（D-D） on pulmonary embolism （PE）. Methods Subjects were selected from patients admitted to department of cardiology with clinically confirmed PE and control group selected from people with medical examination, Clinical Data including MPV and D- D were collected for each people. Results A total of 284 cases were analyzed, including 184 patients in PE group and 100 people in the control group, Ratio of smokers, MPV and D-D level in the PE group was significantly higher than in the control group （P 〈 0. 05 ） ;In multivariate logistic regression analysis, MPV and D-D level were found to be independent predictors of PE. Combine with MPV and D-D level compared with one of them,Combine method true positive（χ2 = 38.18 ,P = 0. 031 ） , true negative （ χ2 = 56.02, P = 0. 012 ） is a significant comparative difference. Conclusion Combination with MPV and D-D is a helpful method for the diagnosis of PE.
出处
《血栓与止血学》
2017年第3期421-423,427,共4页
Chinese Journal of Thrombosis and Hemostasis
