摘要
目的探讨血管内支架成形术对严重颈动脉狭窄所致的短暂性脑缺血发作(TIA)患者临床疗效、术后并发症及预后的影响。方法回顾性分析本院2013年12月~2015年12月收治的72例TIA患者的临床资料,均为严重颈动脉狭窄所致,随机分为对照组(35例)和观察组(37例),分别给予常规药物治疗和血管内支架成形术治疗。结果手术前后分别对观察组患者进行颈动脉狭窄段管腔内径测量,经测量和比较可得存在明显差异,手术后管腔内径明显增大(P<0.05);治疗前与治疗后1个月、3个月、6个月,分别对两组进行NIHSS评分,经评分和比较可得,治疗后1个月、3个月、6个月,与本组治疗前进行组内比较存在统计学差异,P<0.05;且对照组与观察组同一时间进行组间比较也存在统计学差异(P<0.05)。术后随访6个月,所有患者均获得随访,随访率100.0%。经随访,术中有1例发生基底节栓塞,经积极治疗后痊愈。1例患者出现再狭窄,再狭窄率为2.70%(1/37)。结论对严重颈动脉狭窄所致的TIA患者实施血管内支架成形术治疗效果确切,术后并发症少,可显著改善预后。
Objective To explore the effect of endovascular stent angioplasty on the clinical outcome, postoperative complications and prognosis of patients with transient ischemic attack （ TIA ） caused by severe carotid stenosis. Methods A retrospective analysis of our hospital in December 2013 -2015 in December admitted to the clinical data of 72 patients with TIA were caused by severe carotid artery stenosis, were randomly divided into control group （35 cases）and observation group （37 cases）, were given routine drug treatment and endovaseular stent forming surgery. Results Before and after operation respectively. The patients in the observation group were measured carotid artery stenosis diameter, by measurement and comparison have obvious differences, lumen diameter increased significantly after surgery （ P 〈 0.05 ） ; before treatment and 1 months,3 months and 6 months after treatment, respectively, of the two groups were evaluated by NIHSS. The score and the comparison between available, 1 months,3 months and 6 months after treatment, there were significant differences within the group compared with the group before treatment （ P 〈 0.05 ） ; and the control group and the observation group at the same time were compared between the two groups have significant difference,P 〈 0.05. All patients were followed up for 6 months. The follow-up rate was 100%After follow-up, 1 cases of basal ganglia embolization occurred in the operation. Restenosis occurred in 1 patients,the restenosis rate was 2. 70% （1/37）. Conclusion Endovascular stenting for patients with TIA caused by severe carotid stenosis is effective,with less complications and significantly improved prognosis.
出处
《血栓与止血学》
2017年第4期588-590,共3页
Chinese Journal of Thrombosis and Hemostasis
基金
国家自然科学基金重点国际(地区)合作研究项目(项目编号:81520108011)
