摘要
目的探讨梅毒性脉络膜视网膜炎患者眼底光学相干断层扫描(optical coherence tomography,OCT)特征。方法采用回顾性研究,纳入梅毒性脉络膜视网膜炎患者58例88眼,进行眼底荧光血管造影(fluorescence fundus angiography,FFA)、眼底吲哚青绿造影(indocyanine green angiography,ICGA)和OCT检查,以及快速血浆反应素环状卡片试验(rapid plasma reagin test,RPR)和梅毒螺旋体颗粒凝集试验(treponema pallidum particle agglutination test,TPPA),后给予驱梅治疗并随访。结果本研究中87眼视网膜色素上皮层针尖样、锯齿样突起,86眼视网膜外界膜及肌样体带、椭圆体带结构不清、消失,68眼玻璃体内高反射点,16眼视网膜浅脱离。驱梅治疗后,87眼中79眼视网膜色素上皮层针尖样、锯齿样突起完全恢复,86眼中62眼视网膜外界膜及肌样体带、椭圆体带部分显示,16眼视网膜浅脱离均恢复。结论梅毒性脉络膜视网膜炎眼底OCT主要特征为受累视网膜色素上皮针尖样、锯齿样突起,外界膜及肌样体带、椭圆体带显示不清或消失以及视网膜浅脱离,早期正规治疗后上述特征恢复良好。
Objective To discuss the optical coherence tomography （OCT） characteristics in patients with syphilitic chorioretinitis. Methods This was a retro- spective cohort study. 58 patients （88 eyes） with syphilitic chorioretinitis were includ- ed. The fluorescence fundus angiography （FFA）, indocyanine green angiography （IC- GA） and OCT examination were performed, and the rapid plasma regain test （RPR） and treponema pallidum particle agglutination test （TPPA） were also made. The treat- ment response and follow up results were analyzed. Results In this study, 87 eyes re- presented as needle like projections of the retinal pigment epithelium, 86 eyes represen- ted as retinal external membrane and myoid, ellipsoid structure was unclear or disap- pear,68 eyes represented as high reflection points within the vitreous body, 16 eyes re- presented as shallow retinal detachment. After treatment, the needle like projections of the retinal pigment epithelium were fully restored in 79 eyes, retinal external membrane and myoid, ellipsoid structure were partial displayed in 62 eyes, and shallow retinal de- tachment were fully restored in 16 eyes. Conclusion The manifestations of OCT in patients with syphilitic chorioretinitis include needle like projections of the retinal pig- ment epithelium, unclear or disappear retinal external membrane and myoid, ellipsoid structure, high reflection points within the vitreous body and shallow retinal detach- ment. The above manifestations of OCT can be recovered significantly with treatment.
出处
《眼科新进展》
CAS
北大核心
2017年第6期565-568,共4页
Recent Advances in Ophthalmology
