摘要
目的观察医用透明质酸钠预防剖宫产术后组织粘连的效果。方法将株州市中心医院2008年3月-2015年3月行2次剖宫产的205例产妇随机分为对照组103例和观察组102例。对照组行第1次剖宫产术后常规关闭腹腔,观察组在手术部位及附近组织涂抹透明质酸钠,然后统计及比较两组产妇的盆腹腔粘连程度、粘连症状和并发症、再次手术时间及难度。结果观察组粘连发生程度及粘连发生率低于对照组,经比较差异有统计学意义(P<0.05)。观察组术后发热时间、肠鸣音恢复时间和肛门排气时间均短于对照组,经比较差异有统计学意义(P<0.05),其在术后3、6个月发生肠粘连的例数少于对照组,经比较差异有统计学意义(P<0.05)。观察组再次手术时间短于对照组,经比较差异有统计学意义(P<0.05)。结论应用透明质酸钠能有效治疗和预防剖宫产术后组织粘连,使孕产妇获益,值得应用推广。
Objective To observe the clinical effect of medical sodium hyaluronate in preventing tissue adhesion after cesarean section. Methods A total of 205 women receiving the second cesarean section in the hospital from March 2008 to March 2015 were selected and randomly divided into control group （103 cases） and observation group （102 cases） . The women in control group were treated with routine abdominal closure after the first operation, and the women in observation group were treated with sodium hyaluronate in the surgical site and adjacent tissue. The degree of abdominopelvic cavity adhesion, adhesion symptoms, complications, the time of secondary cesarean section and difficulties in the two groups were compared. Results The degree and incidence rate of adhesion in observation group were statistically significantly lower than those in control group （P〈0. 05） . The fever time, borborygmus recovery time, and exhausting time after operation in observation group were statistically significantly shorter than those in control group （P〈0. 05 ） . The number of intestinal adhesion at 3 and 6 months after operation in observation group were statistically significantly less than those in control group （ P〈0. 05 ） . The time of secondary cesarean section in observation group was statistically significantly shorter than that in control group （P〈0. 05） . Conclu- sion Sodium hyaluronate can effectively treat and prevent tissue adhesion after cesarean section, which is good for the pregnant women, and it is worthy of application and promotion.
出处
《中国妇幼保健》
CAS
2017年第11期2473-2475,共3页
Maternal and Child Health Care of China
基金
吴阶平医学基金会临床科研专项资助基金(2011-427-2010)
关键词
透明质酸钠
粘连
剖宫产
Sodium hyaluronate
Adhesion
Cesarean section
