期刊文献+

腹腔镜下子宫肌瘤剔除术与高强度聚焦超声治疗子宫肌瘤的临床疗效比较 被引量:34

Clinical Effect of Laparoscropic Myomectomy or High-intensity Focused Ultrasound for Uterine Fibroid
下载PDF
导出
摘要 目的比较腹腔镜下子宫肌瘤剔除术(LM)与高强度聚焦超声(HIFU)治疗子宫肌瘤的临床疗效。方法按照手术方式将95例子宫肌瘤患者分为观察组(HIFU)45例和对照组(LM)50例,观察组行HIFU治疗,对照组患者行LM治疗,比较两组手术效果。结果观察组患者手术时间、术中出血量、住院时间、术后恢复正常生活时间均显著优于对照组,手术费用显著高于对照组,差异有统计学意义(P<0.05);两组患者术后并发症发生率和复发率比较,差异无统计学意义(P>0.05);观察组患者术后3个月月经异常和腰痛改善率显著低于对照组,差异有统计学意义(P<0.05);两组患者术后6个月各临床症状改善率对比,差异无统计学意义(P>0.05)。结论 HIFU治疗子宫肌瘤临床效果确切,具有无创、术后恢复快等优点,但临床症状改善较为缓慢,治疗花费也较高,需根据实际情况进行选择。 Objective To compare the clinical effect of laparoscropic myomectomy (LM) or high-intensity focused uhra- sound (HIFU) for uterine fibroid. Methods 95 cases of patients with uterine fibroid were divided into the observation group ( HIFU ,45 cases) and the control group( LM ,50 cases). The observation group were treated by HIFU. The control group were treated by LM. The clinical effect were observed. Results The level of operation time, bleeding volume, hospital stays and time back to normal life of the observation group were lower than the control group ( P 〈 0.05 ) ; The operation cost of the observation group were higher than the control group( P 〈 0.05 ) ;There were no significant difference in the rate of complication and relapse between the 2 groups ( P 〉 0.05 ) ; The rate of menstruation disorder and lumbago improved 3 months postoperation of the observation group were lower than the control group ( P 〈 0.05 ) ; There were no significant difference in the rate of every clinical symptoms improved 6 months postoperative between the 2 groups ( P 〉 0.05 ). Conclusion It has exact therapeutic effect for the patients with uterine fibroid by HIFU. The advantage are noninvasive and short recovery time. But it needs long time to improve the clinical symptoms. The operation cost is high. It needs according to the actual situation to choose.
作者 郑献红
出处 《实用癌症杂志》 2017年第7期1186-1188,共3页 The Practical Journal of Cancer
关键词 子宫肌瘤 腹腔镜下子宫肌瘤剔除术 高强度聚焦超声 Uterine fibroid Laparoscropic myomectomy(LM) High-intensity focused uhrasound(HIFU)
  • 相关文献

参考文献7

二级参考文献79

  • 1马慧,武力,沈旺,王新允.子宫内膜间质肉瘤43例临床病理分析[J].实用癌症杂志,2014,29(3):317-318. 被引量:3
  • 2熊正爱,杜永洪,龚晓波,王雁琴,罗天友,丁勇利,王智彪.MRI在HIFU治疗后随访中的作用[J].重庆医科大学学报,2005,30(3):452-455. 被引量:10
  • 3任小龙,周晓东,张军,何光彬,王磊,罗文,郑敏娟,张民.超声造影评价高强度聚焦超声治疗子宫肌瘤早期疗效的价值:与增强MRI对照研究[J].中华超声影像学杂志,2007,16(2):151-153. 被引量:13
  • 4Flake GP, Andersen J, Dixon D. Etiology and pathogenesis of u- terine leiomyomas: a review[ J]. Environ Health Perspect,2003, 111(8) : 1037-1054.
  • 5Greathouse KL, Bredfeldt T, Everitt JI,et al. Environmental es- trogens differentially engage the histone methyhransferase EZH2 to increase risk of uterine tumorigenesis [ J]. Mol Caneer Res, 2012,10(4) :546-557.
  • 6Walker CL. Epigenomic reprogramming of the developing repro- ductive tract and disease susceptibility in adulthood [ J ]. Birth Defects A Clin Mol Teratol,2011,91 (8) :666-671.
  • 7Lee EJ, Kong G, Lee SH, et al. Profiling of differentially ex- pressed genes in human uterine leiomyomas [ J ]. Int J Gynecol Cancer,2005,15 ( 1 ) : 146-154.
  • 8Hsieh YY, Chang CC,Tsai CH, et al. Interleukin (IL)-12 recep- tor betal codon 378 G homozygote and allele,but not IL-1 (beta- 511 promoter, 3953 exon 5, receptor antagonist) , IL-2 114, IL-4- 590 intron 3, IL-8 3 "-UTR 2767, and IL-18 105, are associated with higher susceptibility to leiomyoma [ J ]. Fertil Steril,2007, 87(4) :886-895.
  • 9Okolo S. Incidence, aetiology and epidemiology of uterine fibroids [ J]. Best Pract Res Clin Obstet Gynecol, 2008,22 (4):571- 588.
  • 10Wang L, Huang H, Liu D, et al. Evaluation of 14-3-3 protein family levels and associated receptor expression of estrogen and progesterone in human uterine leiomyomas[ J]. Gynecol Endocri- nol,2012,28 (8) :665-668.

共引文献417

同被引文献256

引证文献34

二级引证文献120

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部