摘要
目的分析艾迪注射液预防妇科恶性肿瘤化疗患者抑郁的效果。方法选取我院2015年1月～2016年6月收治的80例妇科恶性肿瘤患者作为研究对象，将其随机分为观察组和对照组各40例。两组患者均行化疗，观察组患者在化疗期间给予艾迪注射液。两组患者在化疗初期以及化疗2周期后，采用抑郁自评量表（SDS）以及欧洲癌症研究治疗组织癌症患者生命质量调查表（EORTC）的核心量表（QLQ—C30）分别对两组患者抑郁发生率，以及各项生命质量指标进行评价分析。结果化疗2周期后两组患者总健康状况均下降，观察组下降程度小于对照组（P〈0．05）。化疗后2周期后，观察组角色功能、疲倦、疼痛、食欲减退、失眠、腹泻、便秘明显低于对照组；观察组气短明显高于对照组（P〈0．05）。化疗2周期后，观察组的抑郁发生率为25％，明显低于对照组的50％，差异具有统计学意义（P〈0．05）。结论艾迪注射液预防妇科恶性肿瘤化疗患者抑郁的效果优于单纯化疗，能有效改善抑郁症状，提高生存质量。
Objective To analyze the effects of Addie injection on prevention of depression in patients with gynecological malignant tumor. Methods 80 patients with gynecological malignant tumor from Jan. 2015 to Jun. 2016 were randomly divided into observation group （ n = 40） and control group （ n = 40）. All patients were treated with chemotherapy. Patients in observation group were given Addle injection during chemotherapy. Self - rating depression scale （SDS） and core scale （ QLQ - c30） of European organization for research and treatment of cancer patients with quality of life questionnaire（ EORTC）were used at the beginning of chemotherapy and after 2 cycles of chemotherapy for all patients. The incidence of depression and life quality indexes were evaluated and analyzed. Results Total health in observation group was significantly better than that in control group after 2 cycles of chemotherapy （P 〈 0.05）. Role function, fatigue, pain, anorexia, insomnia, diarrhea and constipation were lower and shortness of breath was higher in observation group than those in control group after 2 cycles of chemotherapy（P 〈0.05 ）. The incidence of depression （ 25 % ） in observation group was significantly lower than that in control group （50%） （P 〈 0.05 ）. Conclusion Addie injection is more effective than chemotherapy alone in the prevention of depression in patients with gynecological malignant tumor,which can effectively improve symptoms of depression and the quality of life.
作者
薛聪玲
Xue Congling(Department of Gynecology, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang 471009, China)
出处
《医学新知》
CAS
2017年第3期253-254,257,共3页
New Medicine
关键词
妇科恶性肿瘤
化疗
抑郁
艾迪注射液
治疗效果
Gynecologic malignant tumor
Chemotherapy
Depression
Addie injection
Therapeutic effect
