摘要
目的探讨微创手术对直肠癌患者免疫功能的影响。方法按照随机分配原则将100例患者平均分成两组。实验组行腹腔镜手术治疗,对照组行开腹手术治疗。结果实验组术中出血量、胃肠道恢复时间、术后住院时间均优于对照组,两组比较差异有统计学意义(P<0.05);对照组手术时间少于实验组,差异有统计学意义(P<0.05);两组患者术后1、3、5 d C-反应蛋白和白细胞介素-6均增高,差异有统计学意义(P<0.05);两组患者术后1、3、5 d CD3^+、CD4^+、CD8^+和CD4^+/CD8^+水平比较差异有统计学意义(P<0.05)。结论腹腔镜手术对直肠癌患者免疫功能的影响小,值得在临床上推广使用。
Objective To investigate the minimally invasive operation of minimally invasive operation of direct influence on the immune function of patients with rectal cancer.Methods One hundred patients were divided into two groups according to random distribution principle.The experiment group was treated by laparoscopic operation, the control group was treated by open operation.Results The intraoperative bleeding, gastrointestinal recovery time, postoperative hospitalization time of the experiment group were better than those of the control group（P〈0.05）;the operation time in the control group was less than that in the experiment group（P〈0.05）.The levels of C-reaction protein（CRP） and interleukin-6（IL-6） 1, 3, 5 d postoperative of the two groups were increased（P〈0.05）;postoperative 1, 3, 5 d, the differences of CD3＋,CD4＋,CD8＋ and CD4＋/CD8＋ levels between the two groups were significant （P〈0.05）.Conclusion Laparoscopic operation has smaller effect on immune function in patients with rectal cancer, it is worth to be popularizing in clinic.
出处
《临床医学》
CAS
2017年第6期18-20,共3页
Clinical Medicine
关键词
微创手术
直肠癌
免疫功能
腹腔镜手术
Minimally invasive operation
Rectal cancer
Immune function
Laparoscopic operation
