摘要
目的探讨不同心功能情况对经皮冠状动脉介入治疗(PCI)术后1年出血事件发生情况的影响。方法回顾性分析2007—2014年在沈阳军区总医院住院治疗并行PCI术的纽约心脏病协会(NYHA)心功能分级Ⅰ~Ⅲ级及心功能正常的冠心病患者的临床资料。所有入选患者经过倾向性评分匹配后,最终筛选出4 145对(8 290例)患者。根据NYHA心功能分级标准将所有患者分为症状组(NYHA分级Ⅱ~Ⅲ级,n=4 145)及对照组(心功能正常及NYHA分级Ⅰ级患者,n=4 145)。所有患者均行PCI治疗,随访1年,观察并比较两组患者出院1年出血事件的发生情况。结果两组患者一般资料、造影结果及介入手术资料、全部出血事件比较,差异均无统计学差异(P>0.05);两组患者出血学术研究联合会(BARC)2~5级、BARC 3~5级出血事件发生率比较,差异也无统计学差异(P>0.05)。结论单中心资料表明,心功能严重程度不影响PCI术后患者出血事件的发生。
Objective To investigate the effect of different cardiac function on the occurrence of bleeding after pereutaneous coronary intervention（PCI） for 1 year. Methods A retrospective study was performed on patients with coronary heart disease who were admit- ted from 2007 to 2014 in the treatment of PCI, and the conditions of the entry group were according to heart function（ NYHA class Ⅰ - Ⅲ ）. All 8 290 patients were divided into the symptom group（ NYHA class Ⅱ -Ⅲ ,n =4 145 ） and the control group（ including normal heart function and NYHA I, n = 4 145 ）. All patients were discharged after pereutaneous coronary intervention （PCI）. Patients were fol- lowed up for 1 years. The incidence of bleeding events in the two groups were observed and compared. Results There was no signifi- cant difference in baseline data, angiographic results, interventional procedures and total bleeding events between the two groups（ P 〉 0.05 ）. Comparison of BARC 2-5 bleeding events and the 3-5 level had no statistically significant difference（ P 〉 0. 05 ）. Conclusion The single-central data showed that the severity of cardiac function did not affect the occurrence of bleeding events after PCI.
出处
《临床军医杂志》
CAS
2017年第6期629-631,660,共4页
Clinical Journal of Medical Officers
关键词
经皮冠状动脉介入
心功能不全
出血事件
Percutaneous coronary intervention
Cardiac insufficiency
Bleeding events
