摘要
目的 探究自拟宣肺止咳平喘汤联合布地奈德治疗慢性阻塞性肺疾病急性加重期（acute exacerbation of chronic obstructive pulmonary disease,AECOPD）临床疗效.方法 选取2014年6月-2016年6月本院收治的84例AECOPD患者随机分为观察组和对照组,给予对照组患者布地奈德治疗,观察组在对照组基础上联合自拟宣肺止咳平喘汤治疗,比较2组患者临床疗效、治疗前后炎性因子水平及肺功能指标水平.结果 观察组临床治疗总有效率显著高于对照组（P〈0.05）;观察组治疗后IL-6、TNF-α水平显著低于对照组（P〈0.05）,FEV1%、FEV1/FVC水平显著高于对照组（P〈0.05）.结论 自拟宣肺止咳平喘汤联合布地奈德治疗ARCOPD疗效显著,能有效改善患者炎性反应和肺功能.
Objective To investigate the clinical effect of Xuanfei Zhike Pingchuan decoction combined with budesonide in the treatment of acute exacerbation of chronic obstructive pulmonary disease （AECOPD）.Methods84 patients with AECOPD in our hospital from June 2014 to June 2016 were selected and randomly divided into the observation group and the control group.The control group was given budesonide and the observation group on the basis of the control group was given Xuanfei Zhike Pingchuan decoction.The clinical efficacy, the levels of inflammatory cytokines and pulmonary function were compared between the two groups.ResultsThe total effective rate for clinical treatment in the observation group was significantly higher than the control group（P〈0.05）.The levels of IL-6 and TNF-α in the observation group after treatment were significantly lower than the control group （P〈0.05）,while the levels of FEV1% and FEV1/FVC were obviously higher than the control group （P〈0.05）.ConclusionXuanfei Zhike Pingchun decoction combined with budesonide on ARCOPD has a significantly curative effect and can effectively improve the inflammatory response and recovery of pulmonary function.
作者
费建荣
朱佳威
FEI Jian-rong ZHU Jia-wei(Department of Internal Medicine, People＇s Hospital of Wuxing District, Huzhou City, Huzhou 313008, China Department of Emergency Medicine, People＇s Hospital of Wuxing District, Huzhou City, Huizhou 313008, China)
出处
《中国生化药物杂志》
CAS
2017年第6期147-148,共2页
Chinese Journal of Biochemical Pharmaceutics
关键词
宣肺止咳平喘汤
布地奈德
炎症因子
肺功能
Xuanfei Zhike Pingchuan decoction
budesonide
inflammatory factors
pulmonary function
