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2组米非司酮配合卡孕栓联合心理干预终止瘢痕子宫妊娠的疗效评价 被引量:1

Efficacy of mifepristone combined with psychological intervention in the treatment of uterine scar pregnancy
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摘要 目的 研究分析米非司酮配合卡孕栓联合心理干预终止瘢痕子宫妊娠的疗效评价.方法 选取浙江省玉环县中医院于2015年3月-2016年12月期间瘢痕子宫妊娠终止的产妇60例做本次研究研究过程中的实验组,选择无瘢痕子宫妊娠的产妇60作为本次研究过程中的对照组.相关医护人员需加强与患者的沟通,了解患者内心的负面想法,利用自己的专业知识为患者解决疑惑,消除不安和焦虑,提高患者的治疗依从性,建立患者治疗信心;实验组与对照组患者均进行米非司酮治疗,口服使用,患者在药物治疗的第3天应实验卡孕栓进行服用,该药选取空腹用药,在阴道后穹隆上放置.比较分析实验组与对照组患者的治疗效果以及不良反应情况.结果 经过治疗后,实验组60例患者中,治疗总有效例数为55例,无效例数为5例,治疗有效率为91.7%.对照组60例患者中,治疗总有效例数为48例,无效例数为12例,治疗有效率为80.0%.可得,实验组治疗效果显著高于对照组患者,差异具有统计学意义(P〈0.05).治疗后,实验组妊娠产物排出时间以及阴道出血量和宫缩发动时间与对照组患者相比,差异无统计学意义.对照组患者中,发生不良反应的例数为8例,概率为13.3%,实验组患者中,发生不良反应的例数为4例,概率为6.7%.可得,实验组不良反应发生概率显著低于对照组患者,具有统计学意义(P〈0.05).结论 米非司酮配合卡孕栓治疗联合心理干预终止瘢痕子宫效果较好,不良反应发生率较低,治疗有效率较高,安全性较高,具有临床进一步推广和应用的意义. Objective To evaluate the efficacy of mifepristone combined with cardiopulmonary suppository combined with psychological intervention in the termination of scar uterine pregnancy.Methods60 cases of maternal women with scarring uterine pregnancy during our period from March 2015 to December 2016 were selected as the experimental group in the course of this study.Maternal 60 with no scarring uterine pregnancy was selected as the control in this study group.Related medical staff need to strengthen communication with patients, understand the negative thoughts of the patient's heart, use their expertise to solve doubts for patients, eliminate anxiety and anxiety, improve patient treatment compliance, the establishment of patient treatment confidence;experimental group and control group of patients Were treated with mifepristone, oral use, the patient in the third day of drug treatment should be tested card pregnant suppository to take, the drug selected fasting medication, placed in the vagina on the dome.To compare the therapeutic effect of the experimental group and the control group and the adverse reaction.ResultsAfter treatment, 60 cases in the experimental group, the total effective number of cases in the treatment of patients with a total of 55 cases, the number of invalid cases in the treatment of patients, the effective rate was 91.7%.The control group of 60 patients, the total effective number of cases for the treatment of 48 cases, the number of invalid cases in the treatment of patients, the effective rate was 80.0%.The results showed that there was significant difference between the experimental group and the control group (P〈0.05).After treatment, there was no significant difference in the time of vaginal discharge, the amount of vaginal bleeding and the time of uterine contraction.In the control group, there were 8 cases of adverse reactions, the probability was 13.3%, in the experimental group, the number of cases of adverse reactions occurred in the number of cases, the probability was 6.7%.There was significant difference between the experimental group and the control group in the incidence of adverse reactions(P〈0.05).ConclusionMifepristone combined with carboprost suppository in the treatment of psychological intervention combined with the termination of good uterine scar effect, low incidence rate of adverse reaction, high treatment efficiency, high safety, with further clinical promotion and application significance.
作者 李海珍 LI Hai-zhen(Department of Obstetrics and Gynecology, Yuhuan County, Yuhuan 317600, China)
出处 《中国生化药物杂志》 CAS 2017年第6期212-214,共3页 Chinese Journal of Biochemical Pharmaceutics
关键词 米非司酮 卡孕栓 心理干预 瘢痕子宫妊娠 疗效 suppository psychological intervention scar uterine pregnancy curative effect
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