摘要
目的观察鼓气通魄汤配合脐贴联合莫沙比利治疗老年慢性功能性便秘(气虚型)的临床疗效及安全性。方法 86例患者随机分为2组。对照组42例,给予莫沙比利治疗,观察组44例,采用莫沙比利联合鼓气通魄汤(黄芪、党参、白术、升麻、柴胡、炙甘草、杏仁、郁李仁、桃仁)并配合脐贴的方法治疗。2组疗程均为28 d(4周)。观察比较2组的短期、长期疗效及不良反应的发生情况。结果观察组和对照组治疗前后总积分比较,差异均有统计学意义,2组在治疗后第7天、14天、21天、28天便秘症状总积分与治疗前比较,差异具有统计学意义。3个月后随访时,观察组的总有效率为95.45%,对照组的总有效率为66.67%,观察组疗效优于对照组,差异有统计学意义(P<0.05)。观察组和对照组的不良反应发生率分别为4.55%和38.10%,差异有统计学意义(P<0.05),观察组的不良反应发生率更低。结论鼓气通魄汤配合脐贴联合莫沙比利治疗气虚型的老年慢性功能性便秘疗效确切。
Objective To observe the clinical efficacy and safety of theGuqi Tongpo decoction combined with umbilical paste with Mosapride therapy in elderly patients with chronic functional constipation （Deficiency）.Methods 86 patients were randomly divided into two groups. 42 patients in the control group were treated with Mosapride, 44 patients in the observation group were treated with Mosapride joint flavoredGuqi Tongpo decoction （Drug composition：Huangqi,Dangshen, Baizhu, Shengma, Chaihu, Zhigancao, Xingren, Yuliren, Taoren） and umbilical paste. The treatment lasted 28 d （4 weeks）. The two groups were observed and compared with the short-term and long-term efficacy and the incidence of adverse.Results Observation group and control group＆#39;s points before and after treatment, the difference was statistically significant. Compared with before treatment the reduce score in constipation symptom between the two groups in the 7 d, 14 d, 21 d, 28 d, the difference was statistically significant. When the 3 months follow-up, the total effective rate of the observation group is 95.45%, the total effective rate of the control group is 66.67%, compared with the control group, the observation group has better efficacy, the difference was statistically significant （P〈0.05）. The adverse reactions incidence of the observation group and the control group were 4.55% and 38.10%, and the difference was statistically significant （P〈0.05）, the adverse reactions incidence of the observation group was lower.Conclusion TheGuqi Tongpo decoction combined with umbilical paste with Mosapride therapy for the elderly patients with the deficiency of chronic functional constipation is better and relatively safer.
作者
金红艳
JIN Hongyan(Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang 110032, China)
出处
《吉林中医药》
2017年第6期564-567,共4页
Jilin Journal of Chinese Medicine
基金
基金项目:辽宁省科学技术厅辽宁地区中医康复传统疗法的挖掘与整理(2014020048)
关键词
老年人
慢性功能性便秘
气虚型
鼓气通魄汤
脐贴
莫沙比利
elderly
chronic functional constipation
qi deficiency type
Guqi Tongpo decoction
umbilical paste
Mosapride
