摘要
目的探讨来源于妇科而被误诊为消化道癌的肿瘤病理形态及免疫组化特征。方法回顾分析我院3例妇科原发性癌被误诊为消化道癌的病理资料并文献复习。结果 3例均无妇科肿瘤病史,因以消化道为首发症状而被误诊为消化道癌。后经免疫组化证实来源于妇科的转移性癌。其中2例原发于卵巢,1例原发于子宫,以浆液性癌和宫内膜样癌为主要组织类型,分别转移至乙状结肠(1例)、直肠(2例)。结论发生于中老年妇女的下消化道肿瘤,尤其对病史不详、治疗效果不佳时,应排除妇科肿瘤转移的可能,病理诊断应结合临床资料、肿瘤组织形态及免疫组化特征。
Objective To investigate the pathological and immunohistochemical features of the tumors which were misdiagnosed as digestive tract cancer and origined from gynecology. Methods A retrospective analysis of 3 cases of primary gynecological carcinoma was carried out in our hospital that were diagnosed as digestive tract cancer, with literature review. Results The 3 cases had no any history of gynecological tumor, the digestive problem was the first symptom. The metastatic cancer of gynaecologic organs was confirmed by immunohistochemistry. Among them, 2 cases were from ovary and 1 cases was from uterus. Serous carcinoma and endometrial carcinoma were the main types, which were metastazed to sigmoid colon （ 1 cases） and rectum （2 cases）. Conclusion When lower digestive tract tumors occurs in the middle and old aged women, especially without any clear history or effective treatment, the possibility of gynecological tumor metastasis should be excluded. Pathological diagnosis should be combined with clinical data, tumor morphology and immunohistochemical characteristics.
作者
黄璇
张询
HUANG Xuan ZHANG Xun(National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijinf 100021, China)
出处
《诊断病理学杂志》
2017年第6期427-430,共4页
Chinese Journal of Diagnostic Pathology
关键词
妇科恶性上皮性肿瘤
消化道癌
转移
Gynecology malignant carcinoma
Digestive tract cancer
Metastasis
