摘要
牙周炎是一种由多种微生物诱发的慢性炎症性疾病,其造成的牙周组织损伤常与宿主免疫反应所引发的炎症相关。研究认为,患者的免疫状况与牙周炎的发生和发展相关,CD4阳性T淋巴细胞(CD4^+T细胞)可部分反映患者的免疫状况,其与牙周炎的关系为近年来的研究热点。本综述将近年来有关CD4^+T细胞的分化、功能及其与牙周炎关系的相关研究作一综述,旨在阐明CD4^+T细胞在牙周炎的发生、发展中的作用。
Periodontitis,a chronic inflammatory disease caused by a variety of microbes,causes periodontal tissue damage associated with the host immune response inducing inflammation. It′s widely accepted that the occurrence and development of periodontitisis associated with patients′ immune status can be partly reflected by CD4-positive T-lymphocytes（CD4＋T cells）. Their relationship with periodontitis has become a hotspot in recent years. This review summarizes the recent studies on the differentiation and function of CD4＋T cells and their relationship with periodontitis,and aims to elucidate the role of CD4＋T cells in the genesis and progression of periodontitis.
出处
《中华口腔医学研究杂志（电子版）》
CAS
2017年第3期178-183,共6页
Chinese Journal of Stomatological Research(Electronic Edition)
