摘要
目的分析青少年脂肪、肌肉与骨密度的相关性。方法采用美国Norland XR-800双能X线骨密度仪(DXA)及清华同方BCA-2A人体成分仪(BIA),同时测量106例正常青少年志愿者全身骨密度(BMD)、骨矿含量(BMC)、肌肉含量(LM)、脂肪含量(FM),分析全身骨密度与肌肉、脂肪的相关性。结果⑴BIA与DXA在脂肪含量百分比(FM%)、LM测试上无明显差异,但FM和BMC差异显著(P<0.05)。⑵DXA测得男生的全身BMC、LM以及体质量均高于女生,女生的FM高于男生。13~15岁,男女全身BMD无显著性差异;16~17岁,男生全身BMD高于女生。⑶106例志愿者全身BMD与体质量、BMI、LM呈正相关(分别为r=0.772 9,P=0.000 0;r=0.381 2,P=0.000 0;r=0.685 9,P=0.000 0),而与FM的相关性无统计学意义(r=0.158 6,P=0.117 1)。⑷按性别分析,58例男生全身BMD与体质量、BMI、LM、FM均呈正相关(分别为r=0.810 7,P=0.000 0;r=0.491 6,P=0.000 0;r=0.841 8,P=0.000 0;r=0.268 9,P=0.030 9),但全身BMD与FM相关性较低;48例女生全身BMD与体质量、BMI、LM呈正相关(分别为r=0.744 6,P=0.000 0;r=0.223 2,P<0.05;r=0.739 5,P=0.000 0),而与FM的相关性无统计学意义(r=0.261 3,P=0.072 9)。⑸按年龄分析,13~17岁各年龄段的男生全身BMD与体质量、LM均呈正相关,与FM均不相关。女生在13、14岁时,全身BMD与体质量、LM无相关性,15~17岁时全身BMD与体质量、LM呈正相关;各年龄段与FM均无相关性。结论青少年全身BMD与体质量、BMI呈正相关,其中起主要作用的是肌肉组织,与脂肪组织关系不大。青春期的孩子应加强营养、注意体育锻炼,增加肌肉含量及瘦体重,促进骨骼发育,积累更高的峰值骨量,应对老年性骨质疏松。
Objective To analyze the correlation among fat, muscle, and bone mineral density （BMD） in adoles- cents. Methods BMD, bone mineral content （BMC）, lean mass （LM） and fat mass （FM） of the body were measured in 106 adolescent volunteers by dual-energy X-ray absorptiometry （DXA, Norland XR-800） and the body composition analyz- er （BIA, Tsinghua Tong Fang, BCA-2A）. The correlation among BMD, LM and FM was analyzed. Results （1） The fat percentage （FM%） and LM had no significant difference between DXA and BIA but FM and BMC had significant difference between DXA and BIA （P〈O.05）. （2） BMC, LM and body mass of boys were higher than those of girls and FM of girls was higher than that of boys by DXA. BMD between boys and girls was not significantly different in 13-15 years old dolescents but BMD of boys was higher than that of girls in 16-17 years old dolescents. （3） BMD was positively correlated with body mass, BMI, and LM （r=0.772 9, P=0.000 0; r=-.381 2, P=0.000 0; r=0.685 9, P=0.000 0）, but was not correlated with FM （r=0.158 6, P=0.117 1） in 106 adolescents. （4） BMD was positively correlated with body mass, BMI, LM, and FM （r=0.810 7, P=0.000 0; r=0.491 6, P=0.000 0; r=0.841 8, P=0.000 0;r=0.268 9, P=0.030 9） in 58 boys, but the correlation between whole body BMD and FM was lower. BMD was positively correlated with body mass, BMI, and LM （r=0.744 6, P=0.000 0; r=0.223 2, P〈0.05; r=0.739 5, P=0.000 0） but was not correlated with FM （r=0.261 3, P=0.072 9） in 48 girls. （5） BMD of boys was positively correlated with body mass and LM, but was not correlated with FM in 13-17 years old dolescents. BMD of girls was not correlated with body mass and LM in 13-14 years old adolescents, but was positively correlated with those in 15-17 years old dolescents. Inaddtio, BMD was not correlated with FM in all age groups of dolescents. Conclusion BMD is positively correlated with body boss and BMI in adolescents, and the muscle tissue plays a major role. Adolescentchildren should strengthen their nutrition, pay more atten- tion to physical exercise, increase muscle mass and lean body weight, promote bone development, and accumulate higher peak bone mass, which will cope with senile osteo- porosis.
出处
《中国校医》
2017年第6期427-430,共4页
Chinese Journal of School Doctor
基金
清华大学医院科学研究基金(110200004)
