摘要
目的 探讨垂体后叶素在输卵管妊娠腹腔镜保守手术治疗中的临床疗效.方法 选取120例输卵管妊娠患者为研究对象,采用随机数字表法分为观察组和对照组各60例,对照组直接进行腹腔镜保守手术治疗,观察组患者在采用腹腔镜手术前于输卵管系膜中注射垂体后叶素,比较两组患者术中、术后情况,住院时间和术后血人绒毛膜促性腺激素（β-HCG）水平变化情况以及临床疗效.结果 观察组术中出血量、止血时间、手术时间、术后体温、住院时间分别为（21.12±7.86）mL、（3.61±1.68）min、（35.23±10.45）min、（37.35±0.65）℃、（5.64±0.66）d,对照组分别为（97.63±12.11）mL、（13.21±2.91）min、（67.97±20.13）min、（37.62±0.48）℃、（6.75±0.75）d,两组差异均有统计学意义（t=41.049、22.130、11.181、2.588、8.606,均P〈0.05）;观察组术后1 d、4 d、7 d血β-HCG分别为（587.54±105.14）U/L、（141.28±41.21）U/L、（52.47±22.32）U/L,对照组分别为（609.45±114.89）U/L、（238.43±52.16）U/L、（115.33±26.15）U/L,两组术后血β-HCG值均低于术前,两组术后4 d、7 d血β-HCG差异均有统计学意义（t=11.320、14.162,均P〈0.05）;观察组有效率为98.33%,对照组有效率为86.67%,两组差异有统计学意义（χ^2=5.885,P〈0.05）.结论 对经腹腔镜手术治疗的输卵管妊娠患者术前注射垂体后叶素不仅能减少术中的出血量,缩短手术时间和住院时间,降低血β-HCG值,还能提高临床疗效,值得推广和应用.
Objective To explore the curative effect of pituitrin in laparoscopic conservative surgery in the treatment of 60 patients with tubal pregnancy.Methods 120 eggs tube pregnancy patients were selected as the research subjects.According to the random blind points method,they were divided into the observation group and control group,60 cases in each group.The control group was undergoing laparoscopic conservative surgery directly,the observation group was injected pituitrin in the mesosalpinx before laparoscopic surgery.The intraoperative and postoperative condition,postoperative hospitalization days and blood β-human chorionic gonadotrophin（β-HCG） level changes and clinical curative effect were observed and compared in the two groups.Results The intraoperative blood loss,hemostatic time,operation time,postoperative body temperature,hospitalization days of the observation group were （21.12±7.86）mL,（3.61±1.68）min,（35.23±10.45）min,（37.35±0.65）℃,（5.64±0.66）d,respectively,which of the control group were （97.63±12.11）mL,（13.21±2.91）min,（67.97±20.13）min,（37.62±0.48）℃,（6.75±0.75）d,respectively,the differences between the two groups were statistically significant（t=41.049,22.130,11.181,2.588,8.606,all P〈0.05）.The serum β-HCG at 1d,4d,7d after operation of the observation group were （587.54±105.14）U/L,（141.28±41.21）U/L,（52.47±22.32）U/L,respectively,which of the control group were （609.45±114.89）U/L,（238.43±52.16）U/L,（115.33±26.15）U/L,respectively,the serum-HCG values of the two groups were lower than before operation,there were significant difference between the two groups in serum-HCG after operation at 4d and 7d（t=11.320,14.162,all P〈0.05）.The effective rate of the observation group was 98.33%,which of the control group was 86.67%,and the difference between the two groups was statistically significant（χ2=5.885,P〈0.05）.Conclusion The laparoscopic surgical treatment of tubal pregnancy patients with preoperative injection of pituitrin can not only reduce the bleeding in the operation and shorten the operation time and hospital stay,lower blood β-HCG level,also can improve the clinical curative effect,it is worthy of popularization and application.
出处
《中国基层医药》
CAS
2017年第15期2321-2324,共4页
Chinese Journal of Primary Medicine and Pharmacy
